Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50013173
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127407BDBM50127407(5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127427BDBM50127427((S)-4-[2-((S)-2-{(S)-4-[(S)-2-((S)-2-Acetylamino-3...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127433BDBM50127433(5-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127401BDBM50127401(5-{2-[3-Hydroxy-4-(2-hydroxy-2-naphthalen-1-yl-ace...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127400BDBM50127400(4-[2-(2-{4-[2-(2-Bromo-phenyl)-2-hydroxy-acetylami...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127425BDBM50127425(3-[(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-b...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127426BDBM50127426(4-[(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-b...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127430BDBM50127430(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127419BDBM50127419({3-[(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127410BDBM50127410(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{3-h...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127404BDBM50127404(5-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127414BDBM50127414(4-[2-(2-{4-[2-(2-Benzyloxy-phenyl)-2-hydroxy-acety...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127431BDBM50127431(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{3-h...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127435BDBM50127435(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127436BDBM50127436(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127408BDBM50127408(4-(2-{2-[4-(4-Butoxy-benzoylamino)-3-hydroxy-6-met...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127421BDBM50127421(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127422BDBM50127422(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127402BDBM50127402(3-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127409BDBM50127409(4-[(2-{4-[2-(2-Bromo-phenyl)-2-hydroxy-acetylamino...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127417BDBM50127417(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127424BDBM50127424(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127403BDBM50127403(4-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127434BDBM50127434(4-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127416BDBM50127416(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{3-h...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127432BDBM50127432(4-({2-[3-Hydroxy-4-(2-hydroxy-2-naphthalen-1-yl-ac...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127415BDBM50127415(5-{1-[2-(1-{1-[3-Carboxy-1-(1-carboxy-2-phenyl-eth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127405BDBM50127405(4-(2-{2-[4-(2-Biphenyl-4-yl-acetylamino)-3-hydroxy...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127413BDBM50127413(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{3-h...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127411BDBM50127411([1-(1-{1-[1-Hydroxy-2-(1-hydroxycarbamoyl-2-methyl...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127423BDBM50127423((1-{1-[1-(2-{1-[(Benzo[1,3]dioxol-5-ylmethyl)-carb...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127412BDBM50127412((1-{1-[1-(1-Hydroxy-2-{2-methyl-1-[(pyridin-4-ylme...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127406BDBM50127406(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-{2-[2-(3-h...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127429BDBM50127429(5-{2-[3-Hydroxy-4-(2-hydroxy-2-naphthalen-1-yl-ace...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127428BDBM50127428(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{4-[...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127418BDBM50127418({1-[1-(1-{2-[1-(Cyclohexylmethyl-carbamoyl)-2-meth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127437BDBM50127437([1-(1-{1-[2-(1-Butylcarbamoyl-2-methyl-propylcarba...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127420BDBM50127420([1-(1-{1-[2-(1-Cyclohexylcarbamoyl-2-methyl-propyl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed