Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50013387
TargetSerine protease 1(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14543(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129981(2-(5-Chloro-2-oxo-3-phenethylamino-6-phenyl-2H-pyr...)
Affinity DataIC50: <40nMAssay Description:Inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14593(3-amino-5-[1-({[(4-carbamimidoylphenyl)methyl]carb...)
Affinity DataIC50:  64nMAssay Description:Inhibitory activity of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129982((S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)p...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14498(CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14498(CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...)
Affinity DataIC50:  240nMAssay Description:Inhibitory activity of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129981(2-(5-Chloro-2-oxo-3-phenethylamino-6-phenyl-2H-pyr...)
Affinity DataIC50:  420nMAssay Description:Inhibitory activity of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129982((S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)p...)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129981(2-(5-Chloro-2-oxo-3-phenethylamino-6-phenyl-2H-pyr...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibitory activity of the compound against coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50129982((S)-2-(6-benzyl-5-chloro-2-oxo-3-(phenethylamino)p...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity of the compound against coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14543(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14543(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity of the compound against coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14593(3-amino-5-[1-({[(4-carbamimidoylphenyl)methyl]carb...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity of the compound against coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14593(3-amino-5-[1-({[(4-carbamimidoylphenyl)methyl]carb...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed