Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50037173
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50092657(2-[4-(2,4-Diamino-quinazolin-6-ylmethoxycarbonyl)-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101643(6-[(Methyl-phenyl-amino)-methyl]-quinazoline-2,4-d...)
Affinity DataIC50:  69nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50092656(2-[4-(2,4-Diamino-pteridin-6-ylmethoxycarbonyl)-be...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50131565(2-[4-(2,4-Diamino-quinazolin-6-ylmethoxycarbonyl)-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50131564(2-[4-(2,4-Diamino-quinazolin-6-ylmethoxycarbonyl)-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101641(Benzoic acid 2,4-diamino-5-methyl-pyrido[2,3-d]pyr...)
Affinity DataIC50:  230nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101634(Benzoic acid 2,4-diamino-quinazolin-6-ylmethyl est...)
Affinity DataIC50:  390nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101635(2,4-Diamino-quinazoline-6-carboxylic acid benzyl e...)
Affinity DataIC50:  420nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101637(6-Phenylaminomethyl-quinazoline-2,4-diamine | CHEM...)
Affinity DataIC50:  440nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101648(CHEMBL77409 | Terephthalic acid mono-(2,4-diamino-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101642(CHEMBL78631 | Phenyl-acetic acid 2,4-diamino-quina...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101632(Benzoic acid 2,4-diamino-pyrido[2,3-d]pyrimidin-6-...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101640(Benzoic acid 2,4-diamino-pteridin-6-ylmethyl ester...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed