Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 5101
TargetSerotonin N-acetyltransferase(Human)
Johns Hopkins University School of Medicine

LigandPNGBDBM85108(AANAT bisubstrate analog, 3)
Affinity DataKi:  32nM ΔG°:  -43.5kJ/molepH: 6.8 T: 2°CAssay Description:AANAT activity was measured using a spectrophotometric assay in which the enzymatic product CoASH concentration were determined indirectly by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetSerotonin N-acetyltransferase(Human)
Johns Hopkins University School of Medicine

LigandPNGBDBM85109(AANAT bisubstrate analog, 1)
Affinity DataKi:  48nM ΔG°:  -42.5kJ/molepH: 6.8 T: 2°CAssay Description:AANAT activity was measured using a spectrophotometric assay in which the enzymatic product CoASH concentration were determined indirectly by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetSerotonin N-acetyltransferase(Human)
Johns Hopkins University School of Medicine

LigandPNGBDBM85110(AANAT bisubstrate analog, 2)
Affinity DataKi:  67nM ΔG°:  -41.6kJ/molepH: 6.8 T: 2°CAssay Description:AANAT activity was measured using a spectrophotometric assay in which the enzymatic product CoASH concentration were determined indirectly by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetSerotonin N-acetyltransferase(Human)
Johns Hopkins University School of Medicine

LigandPNGBDBM85112(AANAT bisubstrate analog, 5)
Affinity DataKi:  310nM ΔG°:  -37.8kJ/molepH: 6.8 T: 2°CAssay Description:AANAT activity was measured using a spectrophotometric assay in which the enzymatic product CoASH concentration were determined indirectly by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetSerotonin N-acetyltransferase(Human)
Johns Hopkins University School of Medicine

LigandPNGBDBM85111(AANAT bisubstrate analog, 4)
Affinity DataKi:  360nM ΔG°:  -37.4kJ/molepH: 6.8 T: 2°CAssay Description:AANAT activity was measured using a spectrophotometric assay in which the enzymatic product CoASH concentration were determined indirectly by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetSerotonin N-acetyltransferase(Human)
Johns Hopkins University School of Medicine

LigandPNGBDBM85113(AANAT bisubstrate analog, 6)
Affinity DataKi:  840nM ΔG°:  -35.3kJ/molepH: 6.8 T: 2°CAssay Description:AANAT activity was measured using a spectrophotometric assay in which the enzymatic product CoASH concentration were determined indirectly by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetSerotonin N-acetyltransferase(Human)
Johns Hopkins University School of Medicine

LigandPNGBDBM85114(AANAT bisubstrate analog, 7)
Affinity DataKi:  5.84E+3nM ΔG°:  -30.4kJ/molepH: 6.8 T: 2°CAssay Description:AANAT activity was measured using a spectrophotometric assay in which the enzymatic product CoASH concentration were determined indirectly by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed