Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50000036
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000534(CHEMBL24178 | 2-Phenethyl-6-[3-(pyridin-4-ylsulfan...)
Affinity DataIC50: 8nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000536(CHEMBL279934 | 6-Allyl-2-phenethyl-2,3-dihydro-ben...)
Affinity DataIC50: 17nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000526(CHEMBL282530 | 2-Phenethyl-6-(3-phenoxy-propyl)-2,...)
Affinity DataIC50: 23nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000551(CHEMBL416197 | 4-Allyl-2-phenethyl-2,3-dihydro-ben...)
Affinity DataIC50: 25nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000531(CHEMBL25234 | 2-(4-Methoxy-benzyl)-3-methyl-6-prop...)
Affinity DataIC50: 35nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000535(CHEMBL25262 | 3,3-Dimethyl-2-phenethyl-6-(3-phenox...)
Affinity DataIC50: 40nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000538(CHEMBL24633 | 3,3-Dimethyl-6-propyl-2-[2-(pyridin-...)
Affinity DataIC50: 44nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000542(CHEMBL28093 | 4-[3-(5-Hydroxy-2-phenethyl-2,3-dihy...)
Affinity DataIC50: 44nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000527(CHEMBL25515 | 6-[3-(Benzothiazol-2-ylsulfanyl)-pro...)
Affinity DataIC50: 45nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000537(CHEMBL278861 | 2-Phenethyl-4-propyl-6-{3-[4-(5H-te...)
Affinity DataIC50: 45nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000533(CHEMBL25666 | 6-Benzyl-2-phenethyl-2,3-dihydro-ben...)
Affinity DataIC50: 48nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000545(CHEMBL282904 | 8-[3-(5-Hydroxy-2-phenethyl-2,3-dih...)
Affinity DataIC50: 50nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000552(CHEMBL278817 | 2-[2-(4-Chloro-phenyl)-ethyl]-6-(3-...)
Affinity DataIC50: 51nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000524(CHEMBL25530 | 6-Allyl-2-[2-(4-methoxy-phenyl)-ethy...)
Affinity DataIC50: 52nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000528(CHEMBL25194 | 1-{2-Hydroxy-4-[3-(5-hydroxy-2-phene...)
Affinity DataIC50: 53nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 85nMAssay Description:The compound was tested for its inhibitory activity against LTB4 in human PMNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000544(CHEMBL24632 | 3,3-Dimethyl-2-[2-(4-methylsulfanyl-...)
Affinity DataIC50: 92nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000525(CHEMBL24964 | 2-Phenethyl-6-(3-phenoxy-propyl)-4-p...)
Affinity DataIC50: 127nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000532(CHEMBL280192 | 6-Allyl-2-(4-methoxy-benzyl)-3,3-di...)
Affinity DataIC50: 164nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 320nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000546(CHEMBL423111 | 3,4,5,6-Tetrahydroxy-tetrahydro-pyr...)
Affinity DataIC50: 2.00E+3nMAssay Description:The compound was tested for its inhibitory activity against LTB4 in human PMNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed