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Found 9 Enz. Inhib. hit(s) with all data for entry = 50013787
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM16047((4S)-4-[(2S)-2-[(2R,4S,5S)-5-[(2S)-2-[(2S)-2-[(4S)...)
Affinity DataIC50:  2nMAssay Description:Compound was tested for its inhibitory activity against human beta-Secretase (BACE)More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM16250(CHEMBL290001 | N-(tert-butoxycarbonyl)-L-valyl-N-[...)
Affinity DataIC50:  2nMAssay Description:Compound was tested for its inhibitory activity against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50134706(5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for its inhibitory activity against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50134704(CHEMBL2370886 | Peptide BACE derivative)
Affinity DataIC50:  30nMAssay Description:Compound was tested for its inhibitory activity against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50134705(5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-...)
Affinity DataIC50:  120nMAssay Description:Compound was tested for its inhibitory activity against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127427((S)-4-[(S)-2-((S)-2-{(S)-4-[2-((1S,2S)-2-Acetylami...)
Affinity DataIC50:  300nMAssay Description:Compound was tested for its inhibitory activity against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50134703(1-{2-[6-(Biphenyl-4-ylmethoxy)-1,2,3,4-tetrahydro-...)
Affinity DataIC50:  350nMAssay Description:Compound was tested for its inhibitory activity against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50134705(5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-...)
Affinity DataEC50:  4.00E+3nMAssay Description:Compound was tested for its effective concentration against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50134706(5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Compound was tested for its effective concentration against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed