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Found 15 Enz. Inhib. hit(s) with all data for entry = 50013804
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50:  4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50090528(4-Amino-N-(2,6-bis-dimethylamino-pyrimidin-4-yl)-b...)
Affinity DataIC50:  26.3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134811(3-Benzenesulfonyl-2-methylsulfanyl-pyrimido[2,1-a]...)
Affinity DataIC50:  68.9nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134812(3-Benzenesulfonyl-8-ethyl-2-methylsulfanyl-pyrido[...)
Affinity DataIC50:  70.1nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134809(2-Methylsulfanyl-3-(naphthalene-2-sulfonyl)-pyrido...)
Affinity DataIC50:  79.2nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134810(3-Benzenesulfonyl-7-fluoro-2-methylsulfanyl-pyrido...)
Affinity DataIC50:  87.6nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134808(3-Benzenesulfonyl-9-bromo-7-methyl-2-methylsulfany...)
Affinity DataIC50:  269nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134806((E)-2-Benzenesulfonyl-3-(pyridin-2-ylamino)-acrylo...)
Affinity DataIC50:  524nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50:  860nMAssay Description:Inhibition of recombinant human Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134813(2-Methylsulfanyl-3-(propane-1-sulfonyl)-pyrido[1,2...)
Affinity DataIC50:  3.58E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 3A4 with BFCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 3A4 with BzResMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed