Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50013938
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136106(4-(6-Benzyl-benzo[1,3]dioxol-5-yl)-benzenesulfonam...)
Affinity DataIC50: 50nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 54nMAssay Description:Compound was tested for the inhibition of recombinant human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136109(5-Cyclohexylidenemethyl-6-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 70nMAssay Description:Compound was tested for the inhibition of recombinant human Prostaglandin G/H synthase 2 (COX-2) by enzyme AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136108(5-Cycloheptylidenemethyl-6-(4-methanesulfonyl-phen...)
Affinity DataIC50: 200nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 300nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136107((3-Fluoro-phenyl)-[6-(4-methanesulfonyl-phenyl)-be...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136105(5-Benzyl-6-(4-methanesulfonyl-phenyl)-benzo[1,3]di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.40E+4nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 1 (COX-1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136107((3-Fluoro-phenyl)-[6-(4-methanesulfonyl-phenyl)-be...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 1 (COX-1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136106(4-(6-Benzyl-benzo[1,3]dioxol-5-yl)-benzenesulfonam...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was tested for the inhibition of recombinant human Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 1 (COX-1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136106(4-(6-Benzyl-benzo[1,3]dioxol-5-yl)-benzenesulfonam...)
Affinity DataIC50: 6.00E+4nMAssay Description:Compound was tested for the inhibition of human Prostaglandin G/H synthase 1 (COX-1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136105(5-Benzyl-6-(4-methanesulfonyl-phenyl)-benzo[1,3]di...)
Affinity DataIC50: 6.00E+4nMAssay Description:Compound was tested for in vitro Prostaglandin G/H synthase 1 (COX-1) idetermined in human whole blood by human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for the inhibition of recombinant human Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for the inhibition of recombinant human Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136108(5-Cycloheptylidenemethyl-6-(4-methanesulfonyl-phen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for the inhibition of recombinant human Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50136109(5-Cyclohexylidenemethyl-6-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for in vitro inhibition of recombinant human Prostaglandin G/H synthase 1 (COX-1) by enzyme AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed