Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 1187
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9797(Lysine Sulfonamide 14h | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  0.590nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9782((2S)-6-{2-[benzyl(phenyl)amino]acetamido}-2-[(4-me...)
Affinity DataKi:  0.720nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9804(Lysine Sulfonamide 14m | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  1.10nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9799(Lysine Sulfonamide 14i | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  1.20nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9798(Lysine Sulfonamide 13i | N-[(5S)-6-hydroxy-5-[(4-m...)
Affinity DataKi:  1.40nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9784((2S)-6-[(2S)-2-amino-3-phenylpropanamido]-2-[(4-me...)
Affinity DataKi:  1.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9801(Lysine Sulfonamide 14j | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  1.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9794(Lysine Sulfonamide 14f | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  1.60nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9785((2S)-6-[(2S)-2-(methylamino)-3-phenylpropanamido]-...)
Affinity DataKi:  2.10nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9803(Lysine Sulfonamide 14l | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  2.30nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9802(Lysine Sulfonamide 14k | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  2.30nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9793(2-{[(2,3-dimethoxyphenyl)methyl](phenyl)amino}-N-[...)
Affinity DataKi:  2.40nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9787(Lysine Sulfonamide 14a | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  2.40nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9792(Lysine Sulfonamide 14e | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  2.40nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9796(Lysine Sulfonamide 14g | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  2.90nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9795(2-{[(3,4-dimethoxyphenyl)methyl](phenyl)amino}-N-[...)
Affinity DataKi:  3.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9800(Lysine Sulfonamide 13j | N-[(5S)-6-hydroxy-5-[(4-m...)
Affinity DataKi:  3.90nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9774((2S)-6-[(2S)-2-hydroxy-3-phenylpropanamido]-2-[(4-...)
Affinity DataKi:  6.20nM ΔG°:  -47.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9766((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi:  6.90nM ΔG°:  -47.4kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9806(Lysine Sulfonamide 14n | N-[(5S)-5-[(4-aminobenzen...)
Affinity DataKi:  6.90nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9791(Lysine Sulfonamide 13e | N-[(5S)-6-hydroxy-5-[(4-m...)
Affinity DataKi:  7.30nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9786(2-[benzyl(phenyl)amino]-N-[(5S)-6-hydroxy-5-[(4-me...)
Affinity DataKi:  7.60nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9805(2-{[(3-aminophenyl)methyl](phenyl)amino}-N-[(5S)-6...)
Affinity DataKi:  7.60nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9778((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi:  7.80nM ΔG°:  -47.1kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9783((2S)-6-[(dibenzylcarbamoyl)amino]-2-[(4-methylbenz...)
Affinity DataKi:  8nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9780((2S)-6-{2-[methyl(phenyl)amino]acetamido}-2-[(4-me...)
Affinity DataKi:  12nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9790(2-(diphenylamino)-N-[(5S)-6-hydroxy-5-[(4-methylbe...)
Affinity DataKi:  12nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9775((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi:  14nM ΔG°:  -45.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9789(Lysine Sulfonamide 13c | N-[(5S)-6-hydroxy-5-[(4-m...)
Affinity DataKi:  16nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9776((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi:  18nM ΔG°:  -44.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9773((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi:  18nM ΔG°:  -44.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9777((2S)-6-[2-(benzenesulfonyl)acetamido]-2-[(4-methyl...)
Affinity DataKi:  20nM ΔG°:  -44.7kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9779((2S)-6-[(benzylcarbamoyl)amino]-2-[(4-methylbenzen...)
Affinity DataKi:  32nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9788(Lysine Sulfonamide 13b | N-[(5S)-6-hydroxy-5-[(4-m...)
Affinity DataKi:  52nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9781((2S)-6-{[benzyl(methyl)carbamoyl]amino}-2-[(4-meth...)
Affinity DataKi:  55nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9770((2S)-6-(1,1-diphenylacetamido)-2-[(4-methylbenzene...)
Affinity DataKi:  171nM ΔG°:  -39.3kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9764((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi: >300nM ΔG°: >-37.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9765((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi: >300nM ΔG°: >-37.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9767((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi: >300nM ΔG°: >-37.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9768((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi: >300nM ΔG°: >-37.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9771((2S)-6-(2-benzyl-3,3-dimethylbutanamido)-2-[(4-met...)
Affinity DataKi: >300nM ΔG°: >-37.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9772((2S)-6-{[(benzyloxy)carbonyl]amino}-2-[(4-methylbe...)
Affinity DataKi: >300nM ΔG°: >-37.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9769((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Affinity DataKi: >300nM ΔG°: >-37.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed