Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50037223
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136890BDBM50136890([2-Chloro-4-(4-fluoro-2-methyl-phenylamino)-phenyl...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136887BDBM50136887([4-(2-Amino-phenylamino)-2-chloro-phenyl]-(2-metho...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136897BDBM50136897((2-Chloro-4-phenylamino-phenyl)-o-tolyl-methanone ...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136886BDBM50136886([4-(2-Amino-phenylamino)-2-chloro-phenyl]-o-tolyl-...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136884BDBM50136884((2-Chloro-4-o-tolylamino-phenyl)-o-tolyl-methanone...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136898BDBM50136898([4-(2-Amino-phenylamino)-2-methyl-phenyl]-o-tolyl-...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136900BDBM50136900(1-{2-[3-Chloro-4-(2-methyl-benzoyl)-phenylamino]-p...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15244BDBM15244(cid_3038525 | 5-(2,6-dichlorophenyl)-2-[(2,4-diflu...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136903BDBM50136903([4-(2-Amino-phenylamino)-phenyl]-o-tolyl-methanone...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099331BDBM50099331(CHEMBL279416 | 4-(4-(4-fluorophenyl)-1-(piperidin-...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136885BDBM50136885([4-(2-Amino-4-bromo-phenylamino)-2-chloro-phenyl]-...)
Affinity DataIC50: 39nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136888BDBM50136888({2-[3-Chloro-4-(2-methyl-benzoyl)-phenylamino]-phe...)
Affinity DataIC50: 42nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136899BDBM50136899([4-(2-Amino-phenylamino)-phenyl]-(2-bromo-phenyl)-...)
Affinity DataIC50: 54nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136901BDBM50136901(N-{2-[3-Chloro-4-(2-methyl-benzoyl)-phenylamino]-p...)
Affinity DataIC50: 63nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136895BDBM50136895({4-[(2-Amino-phenyl)-methyl-amino]-2-chloro-phenyl...)
Affinity DataIC50: 101nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136902BDBM50136902([4-(2-Amino-phenylamino)-2-chloro-phenyl]-phenyl-m...)
Affinity DataIC50: 139nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136896BDBM50136896([4-(2-Amino-phenylamino)-3-methyl-phenyl]-o-tolyl-...)
Affinity DataIC50: 143nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136882BDBM50136882([4-(2-Amino-phenylamino)-phenyl]-phenyl-methanone ...)
Affinity DataIC50: 145nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136891BDBM50136891(Phenyl-(4-phenylamino-phenyl)-methanone | CHEMBL15...)
Affinity DataIC50: 193nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136883BDBM50136883([2-Chloro-4-(2-nitro-phenylamino)-phenyl]-o-tolyl-...)
Affinity DataIC50: 437nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136893BDBM50136893([4-(2-Amino-phenylamino)-phenyl]-m-tolyl-methanone...)
Affinity DataIC50: 574nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136892BDBM50136892([4-(2-Amino-phenylamino)-phenyl]-biphenyl-2-yl-met...)
Affinity DataIC50: 811nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136889BDBM50136889(N-[3-Chloro-4-(1-o-tolyl-vinyl)-phenyl]-benzene-1,...)
Affinity DataIC50: 1.55E+3nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136894BDBM50136894(N*1*-[3-Chloro-4-(2-methyl-benzyl)-phenyl]-4-fluor...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed