Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50014032
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137400(((R)-2-Phenyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137398(((R)-2-(4-Hydroxy-phenyl)-1-{3-phenyl-1-[(4-piperi...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137388(((R)-2-Methyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137394(((R)-2-(3H-Indol-3-yl)-1-{3-phenyl-1-[(4-piperidin...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137392([1-(1-Formyl-3-methylsulfanyl-propylcarbamoyl)-3-m...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137393({(S)-1-[(S)-1-Benzyl-2-(4-piperidin-1-yl-phenylami...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137389(((R)-3-Methyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137395({(S)-1-[(S)-1-Benzyl-2-(4-morpholin-4-yl-phenylami...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137390(((R)-3-Methylsulfanyl-1-{3-phenyl-1-[(4-piperidin-...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137400(((R)-2-Phenyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137388(((R)-2-Methyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137392([1-(1-Formyl-3-methylsulfanyl-propylcarbamoyl)-3-m...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137389(((R)-3-Methyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137388(((R)-2-Methyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137398(((R)-2-(4-Hydroxy-phenyl)-1-{3-phenyl-1-[(4-piperi...)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137387(((R)-3-Phenyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137391(((R)-1-{3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137393({(S)-1-[(S)-1-Benzyl-2-(4-piperidin-1-yl-phenylami...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137390(((R)-3-Methylsulfanyl-1-{3-phenyl-1-[(4-piperidin-...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137386(2-{(S)-3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)-...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137387(((R)-3-Phenyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137395({(S)-1-[(S)-1-Benzyl-2-(4-morpholin-4-yl-phenylami...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137397([(S)-1-((S)-1-Benzyl-2-oxo-ethylcarbamoyl)-3-methy...)
Affinity DataKi:  20nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137401({(S)-1-[(S)-1-Benzyl-2-(biphenyl-4-ylamino)-ethylc...)
Affinity DataKi:  32nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137390(((R)-3-Methylsulfanyl-1-{3-phenyl-1-[(4-piperidin-...)
Affinity DataKi:  36nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137394(((R)-2-(3H-Indol-3-yl)-1-{3-phenyl-1-[(4-piperidin...)
Affinity DataKi:  48nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137398(((R)-2-(4-Hydroxy-phenyl)-1-{3-phenyl-1-[(4-piperi...)
Affinity DataKi:  106nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137400(((R)-2-Phenyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  167nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137396([(S)-1-((S)-1-Benzyl-2-phenylamino-ethylcarbamoyl)...)
Affinity DataKi:  230nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137389(((R)-3-Methyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  658nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137401({(S)-1-[(S)-1-Benzyl-2-(biphenyl-4-ylamino)-ethylc...)
Affinity DataKi:  706nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137396([(S)-1-((S)-1-Benzyl-2-phenylamino-ethylcarbamoyl)...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137391(((R)-1-{3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)...)
Affinity DataKi:  2.09E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137394(((R)-2-(3H-Indol-3-yl)-1-{3-phenyl-1-[(4-piperidin...)
Affinity DataKi:  3.36E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137391(((R)-1-{3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)...)
Affinity DataKi:  4.11E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137386(2-{(S)-3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)-...)
Affinity DataKi:  7.84E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137387(((R)-3-Phenyl-1-{3-phenyl-1-[(4-piperidin-1-yl-phe...)
Affinity DataKi:  9.66E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137399(({3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)-methy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against recombinant human cathepsin L (1.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137399(({3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)-methy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137399(({3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)-methy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50137386(2-{(S)-3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed