Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 2095
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

LigandPNGBDBM16250(CHEMBL290001 | tert-butyl N-[(1S)-1-{[(1S)-1-{[(1R...)
Affinity DataIC50: 3nMpH: 4.8 T: 2°CAssay Description:Beta-cleavage ELISA assays were carried out in reaction buffer containing enzyme, substrate MBP-C125, and test compounds. Generated beta-cleaved prod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

LigandPNGBDBM16798((4S)-4-{[(1S)-1-carboxy-2-phenylethyl]carbamoyl}-4...)
Affinity DataIC50: 30nMpH: 4.8 T: 2°CAssay Description:Beta-cleavage ELISA assays were carried out in reaction buffer containing enzyme, substrate MBP-C125, and test compounds. Generated beta-cleaved prod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

LigandPNGBDBM16799((4S)-4-{[(1S)-1-carboxy-2-phenylethyl]carbamoyl}-4...)
Affinity DataIC50: 4.00E+3nMpH: 4.8 T: 2°CAssay Description:Beta-cleavage ELISA assays were carried out in reaction buffer containing enzyme, substrate MBP-C125, and test compounds. Generated beta-cleaved prod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

LigandPNGBDBM16800((4S)-4-{[(1S)-1-carboxy-2-phenylethyl]carbamoyl}-4...)
Affinity DataIC50: 7.50E+3nMpH: 4.8 T: 2°CAssay Description:Beta-cleavage ELISA assays were carried out in reaction buffer containing enzyme, substrate MBP-C125, and test compounds. Generated beta-cleaved prod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed