Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50014305
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140659BDBM50140659([6-(4-Ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrrolo[3,...)
Affinity DataIC50: 40nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140656BDBM50140656([6-(4-Ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrrolo[3,...)
Affinity DataIC50: 75nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140645BDBM50140645(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-p-tolyl-6H-p...)
Affinity DataIC50: 86nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140641BDBM50140641(6-(4-Ethoxy-phenyl)-1-(4-ethyl-phenyl)-4,5,7-trime...)
Affinity DataIC50: 107nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140629BDBM50140629(1-(2-Cyclopentyl-ethyl)-6-(4-ethoxy-phenyl)-4,5,7-...)
Affinity DataIC50: 148nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140664BDBM50140664(1,6-Bis-(4-ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrro...)
Affinity DataIC50: 153nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140642BDBM50140642(6-(4-Ethoxy-phenyl)-1-(4-methoxy-phenyl)-4,5,7-tri...)
Affinity DataIC50: 154nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140631BDBM50140631(1-Cyclopropyl-6-(4-ethoxy-phenyl)-4,5,7-trimethyl-...)
Affinity DataIC50: 170nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140632BDBM50140632([6-(4-Ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrrolo[3,...)
Affinity DataIC50: 170nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140662BDBM50140662(6-(4-Ethoxy-phenyl)-1-isobutyl-4,5,7-trimethyl-6H-...)
Affinity DataIC50: 171nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140647BDBM50140647(6-(4-Ethoxy-phenyl)-1,4,5,7-tetramethyl-6H-pyrrolo...)
Affinity DataIC50: 180nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140643BDBM50140643(1-Cyclopentyl-6-(4-ethoxy-phenyl)-4,5,7-trimethyl-...)
Affinity DataIC50: 185nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140639BDBM50140639(1-Cyclopentylmethyl-6-(4-ethoxy-phenyl)-4,5,7-trim...)
Affinity DataIC50: 211nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140630BDBM50140630(1-Cyclohexyl-6-(4-ethoxy-phenyl)-4,5,7-trimethyl-6...)
Affinity DataIC50: 235nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140644BDBM50140644([6-(4-Ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrrolo[3,...)
Affinity DataIC50: 240nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140653BDBM50140653(6-(4-Ethoxy-phenyl)-1-ethyl-4,5,7-trimethyl-6H-pyr...)
Affinity DataIC50: 250nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140652BDBM50140652(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-(3-methyl-bu...)
Affinity DataIC50: 263nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140628BDBM50140628(6-(4-Ethoxy-phenyl)-1-(3-methoxy-phenyl)-4,5,7-tri...)
Affinity DataIC50: 335nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140636BDBM50140636(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-pentyl-6H-py...)
Affinity DataIC50: 360nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140633BDBM50140633(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-phenyl-6H-py...)
Affinity DataIC50: 382nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140663BDBM50140663([6-(4-Ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrrolo[3,...)
Affinity DataIC50: 440nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140655BDBM50140655(6-(4-Ethoxy-phenyl)-1-(4-fluoro-phenyl)-4,5,7-trim...)
Affinity DataIC50: 528nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140648BDBM50140648(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-(2,4,4-trime...)
Affinity DataIC50: 577nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140649BDBM50140649(1-(2,4-Dimethoxy-phenyl)-6-(4-ethoxy-phenyl)-4,5,7...)
Affinity DataIC50: 597nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140634BDBM50140634(1-(4-Chloro-phenyl)-6-(4-ethoxy-phenyl)-4,5,7-trim...)
Affinity DataIC50: 701nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140640BDBM50140640(6-(4-Ethoxy-phenyl)-1-(2-methoxy-phenyl)-4,5,7-tri...)
Affinity DataIC50: 737nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140654BDBM50140654(1-Biphenyl-4-yl-6-(4-ethoxy-phenyl)-4,5,7-trimethy...)
Affinity DataIC50: 1.26E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140651BDBM50140651(1-(3-Chloro-phenyl)-6-(4-ethoxy-phenyl)-4,5,7-trim...)
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140650BDBM50140650(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-(4-trifluoro...)
Affinity DataIC50: 1.73E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140635BDBM50140635(6-(2-Ethoxy-phenyl)-1,4,5,7-tetramethyl-6H-pyrrolo...)
Affinity DataIC50: 1.85E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140658BDBM50140658(6-(4-Ethoxy-phenyl)-1-methoxy-4,5,7-trimethyl-6H-p...)
Affinity DataIC50: 2.18E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140637BDBM50140637(1-(2-Chloro-phenyl)-6-(4-ethoxy-phenyl)-4,5,7-trim...)
Affinity DataIC50: 4.37E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140657BDBM50140657(1,4,5,7-Tetramethyl-6-(4-propoxy-phenyl)-6H-pyrrol...)
Affinity DataIC50: 5.18E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140660BDBM50140660(6-(4-Methoxy-phenyl)-1,4,5,7-tetramethyl-6H-pyrrol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140661BDBM50140661(6-(3-Ethoxy-phenyl)-1,4,5,7-tetramethyl-6H-pyrrolo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140638BDBM50140638(N-[6-(4-Ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrrolo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140646BDBM50140646([6-(4-Ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrrolo[3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed