Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50003681
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6096(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6096(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6095(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6094(3-quinolinecarbonitrile 18 | 4-[(2,4-dichloro-5-me...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6099(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6094(3-quinolinecarbonitrile 18 | 4-[(2,4-dichloro-5-me...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6095(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6105(6-Methoxy-4-[(5-methoxy-2,4-dimethylphenyl)amino]-...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6103(6-Methoxy-4-[(5-methoxy-2-methylphenyl)amino]-7-[(...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6099(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6101(3-quinolinecarbonitrile 20 | 6-Methoxy-7-[(1-methy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6105(6-Methoxy-4-[(5-methoxy-2,4-dimethylphenyl)amino]-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6100(3-quinolinecarbonitrile 19 | 4-[(2,4-Dichloropheny...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6100(3-quinolinecarbonitrile 19 | 4-[(2,4-Dichloropheny...)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6103(6-Methoxy-4-[(5-methoxy-2-methylphenyl)amino]-7-[(...)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6101(3-quinolinecarbonitrile 20 | 6-Methoxy-7-[(1-methy...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)
Affinity DataIC50: 38nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6098(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6098(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 89nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6106(4-[(2,4-Dichloro-5-ethoxyphenyl)amino]-6-methoxy-7...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6106(4-[(2,4-Dichloro-5-ethoxyphenyl)amino]-6-methoxy-7...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed