Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50048596
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125393(CHEMBL57014)
Affinity DataIC50: 1nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50223758(CHEMBL58925)
Affinity DataIC50: 1nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50132321(CHEMBL298738)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50223762(CHEMBL417588)
Affinity DataIC50: 6nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125395(CHEMBL57259)
Affinity DataIC50: 13nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218997(CHEMBL57824)
Affinity DataIC50: 17nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50149196(CHEMBL56213)
Affinity DataIC50: 20nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218978(CHEMBL57146)
Affinity DataIC50: 32nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218987(CHEMBL56327)
Affinity DataIC50: 36nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50149198(CHEMBL57525)
Affinity DataIC50: 39nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218995(CHEMBL431722)
Affinity DataIC50: 50nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138289(CHEMBL293306)
Affinity DataIC50: 52nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218994(CHEMBL57814)
Affinity DataIC50: 55nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218977(CHEMBL57831)
Affinity DataIC50: 66nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50223757(CHEMBL291976)
Affinity DataIC50: 71nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50132336(CHEMBL407129)
Affinity DataIC50: 102nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218996(CHEMBL57603)
Affinity DataIC50: 130nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218986(CHEMBL56609)
Affinity DataIC50: 150nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218982(CHEMBL299703)
Affinity DataIC50: 160nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50132320(CHEMBL299483)
Affinity DataIC50: 240nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50131338(CHEMBL56082)
Affinity DataIC50: 240nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218988(CHEMBL57253)
Affinity DataIC50: 280nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50132340(CHEMBL299047)
Affinity DataIC50: 300nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218989(CHEMBL56392)
Affinity DataIC50: 300nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50219000(CHEMBL291681)
Affinity DataIC50: 408nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218992(CHEMBL57527)
Affinity DataIC50: 454nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218981(CHEMBL56177)
Affinity DataIC50: 480nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218983(CHEMBL293945)
Affinity DataIC50: 800nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50100963(CHEMBL57658)
Affinity DataIC50: 800nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218999(CHEMBL417762)
Affinity DataIC50: 900nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218984(CHEMBL57413)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125396(CHEMBL291964)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50118678(CHEMBL57415)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50118680(CHEMBL61039)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218979(CHEMBL291456)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50132163(CHEMBL294240)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50118679(CHEMBL56583)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218985(CHEMBL55936)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218980(CHEMBL417598)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218993(CHEMBL418107)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50217048(CHEMBL60923)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50148490(CHEMBL299929)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50148508(CHEMBL57849)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218998(CHEMBL56665)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125397(CHEMBL59484)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142498(CHEMBL418273)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50149197(CHEMBL292225)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218990(CHEMBL300010)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218991(CHEMBL57519)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed