Compile Data Set for Download or QSAR
Report error Found 112 Enz. Inhib. hit(s) with all data for entry = 50037254
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7692(4-{2-[(3Z)-4-(2-methylpropyl)-2-oxo-2,3-dihydro-1H...)
Affinity DataIC50: 1.20nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7693(4-{2-[(3Z)-4-(2-methylprop-1-en-1-yl)-2-oxo-2,3-di...)
Affinity DataIC50: 1.5nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145914(N*4*-(2-Chloro-6-methyl-phenyl)-N*6*,N*6*-diethyl-...)
Affinity DataIC50: 2nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50112911(N-(2-chloro-6-methylphenyl)-6,7-dimethoxyimidazo[1...)
Affinity DataIC50: 2nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50120094(N-(2-chloro-6-methylphenyl)-7,8-dimethoxyimidazo[1...)
Affinity DataIC50: 2nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7725(3-{[4-(Aminosulfonyl)phenyl]hydrazono}-2-oxo-N-(3-...)
Affinity DataIC50: 2.10nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7717(methyl (3Z)-2-oxo-3-{[(4-sulfamoylphenyl)amino]met...)
Affinity DataIC50: 2.10nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7686(4-{2-[(3Z)-5-(1,3-oxazol-5-yl)-2-oxo-2,3-dihydro-1...)
Affinity DataIC50: 2.30nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50120097((7,8-Dimethoxy-imidazo[1,5-a]quinoxalin-4-yl)-(2,6...)
Affinity DataIC50: 2.40nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50112947((6,7-Dimethoxy-imidazo[1,5-a]quinoxalin-4-yl)-(2,6...)
Affinity DataIC50: 2.40nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7691(4-[N'-(4-Isopropyl-2-oxo-1,2-dihydro-indol-3-ylide...)
Affinity DataIC50: 2.5nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7744(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50: 2.80nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50120129((2-Chloro-6-methyl-phenyl)-(6-methoxy-imidazo[1,5-...)
Affinity DataIC50: 3nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145915(N-[4-(2-Chloro-6-methyl-phenylamino)-imidazo[1,5-a...)
Affinity DataIC50: 3nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7695(4-{2-[(3Z)-2-oxo-4-(propan-2-yloxy)-2,3-dihydro-1H...)
Affinity DataIC50: 3.40nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145884(4-(2-Chloro-6-methyl-phenylamino)-imidazo[1,5-a]qu...)
Affinity DataIC50: 4nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145893((2-Chloro-6-methyl-phenyl)-(6-morpholin-4-yl-imida...)
Affinity DataIC50: 4nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7754(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50: 4.30nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7720((3Z)-2-oxo-3-[2-(4-sulfamoylphenyl)hydrazin-1-ylid...)
Affinity DataIC50: 4.5nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7748(N,N-dimethyl-4-({[(12Z)-11-oxo-3-thia-5,10-diazatr...)
Affinity DataIC50: 4.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370316(CHEMBL272667)
Affinity DataIC50: 4.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145922(4-[N'-(4-Iodo-2-oxo-1,2-dihydro-indol-3-ylidene)-h...)
Affinity DataIC50: 4.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7749(2-hydroxy-N-[4-({[(12Z)-11-oxo-3-thia-5,10-diazatr...)
Affinity DataIC50: 4.70nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145924(N*4*-(2-Chloro-6-methyl-phenyl)-N*6*,N*6*-dimethyl...)
Affinity DataIC50: 5nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7758(N-Benzyl-4-{[(7-oxo-6,7-dihydro-8H-[1,3]thiazolo[5...)
Affinity DataIC50: 5.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7747(N-Methyl-4-{[(7-oxo-6,7-dihydro-8H-[1,3]thiazolo[5...)
Affinity DataIC50: 5.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50120106((2-Chloro-6-methyl-phenyl)-(7-morpholin-4-yl-imida...)
Affinity DataIC50: 6nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145891([4-(2-Chloro-6-methyl-phenylamino)-7,8-dimethoxy-i...)
Affinity DataIC50: 6.20nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145897(N*4*-(2-Chloro-6-methyl-phenyl)-imidazo[1,5-a]quin...)
Affinity DataIC50: 7nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7690(4-[2-(4-Ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene...)
Affinity DataIC50: 7.90nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50120122((2-Chloro-6-methyl-phenyl)-(7-methoxy-imidazo[1,5-...)
Affinity DataIC50: 8.70nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7724((3Z)-2-oxo-N-(pyridin-4-ylmethyl)-3-[2-(4-sulfamoy...)
Affinity DataIC50: 8.90nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50112920((2-Chloro-6-methyl-phenyl)-imidazo[1,5-a]quinoxali...)
Affinity DataIC50: 9nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50112931(N-(2,6-dichlorophenyl)imidazo[1,5-a]quinoxalin-4-a...)
Affinity DataIC50: 9nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50120134(N*4*-(2-Chloro-6-methyl-phenyl)-N*7*,N*7*-diethyl-...)
Affinity DataIC50: 9nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145935(4-(2-Chloro-6-methyl-phenylamino)-5-methoxy-imidaz...)
Affinity DataIC50: 9.40nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7755(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50: 9.70nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7708(4-[N -(5-Hydroxy-2-oxo-1,2-dihydro-indol-3-ylidene...)
Affinity DataIC50: 10nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145938(4-(2-Chloro-6-methyl-phenylamino)-7,8-dimethoxy-im...)
Affinity DataIC50: 10nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145937(N*4*-(2-Chloro-6-methyl-phenyl)-N*6*-ethyl-imidazo...)
Affinity DataIC50: 10nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7706(4-[2-(5-Iodo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)...)
Affinity DataIC50: 11nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50120103(N-(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]q...)
Affinity DataIC50: 11nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7699(4-(N -{4-[2-(4-Hydroxyphenyl)-ethyl]-2-oxo-1,2-dih...)
Affinity DataIC50: 12nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7709(4-[N -(5-Methoxy-2-oxo-1,2-dihydro-indol-3-ylidene...)
Affinity DataIC50: 12nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7696(4-{2-[(3Z)-2-oxo-4-phenoxy-2,3-dihydro-1H-indol-3-...)
Affinity DataIC50: 13nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7737(4-[2-(4-Chloro-5-methyl-2-oxo-1,2-dihydro-3H-indol...)
Affinity DataIC50: 13nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50120121((7-Bromo-imidazo[1,5-a]quinoxalin-4-yl)-(2-chloro-...)
Affinity DataIC50: 14nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50145923((6-Bromo-imidazo[1,5-a]quinoxalin-4-yl)-(2-chloro-...)
Affinity DataIC50: 15nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370320(CHEMBL411886)
Affinity DataIC50: 15nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7713(4-{2-[(3Z)-5-methanesulfonyl-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 16nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
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