Compile Data Set for Download or QSAR
maximum 50k data
Found 112 Enz. Inhib. hit(s) with all data for entry = 50037254
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7692(4-[N -(4-Isobutyl-2-oxo-1,2-dihydro-indol-3-yliden...)
Affinity DataIC50:  1.20nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7693(4-{2-[(3Z)-4-(2-methylprop-1-en-1-yl)-2-oxo-2,3-di...)
Affinity DataIC50:  1.5nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50120094((2-Chloro-6-methyl-phenyl)-(7,8-dimethoxy-imidazo[...)
Affinity DataIC50:  2nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50112911((2-Chloro-6-methyl-phenyl)-(6,7-dimethoxy-imidazo[...)
Affinity DataIC50:  2nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145914(CHEMBL85835 | N*4*-(2-Chloro-6-methyl-phenyl)-N*6*...)
Affinity DataIC50:  2nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7725((3Z)-2-oxo-N-(pyridin-3-ylmethyl)-3-[2-(4-sulfamoy...)
Affinity DataIC50:  2.10nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7717(Oxindole-Based Inhibitor 53 | methyl (3Z)-2-oxo-3-...)
Affinity DataIC50:  2.10nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7686(4-[1-(5-Oxazol-5-yl-2-oxo-1,2-dihydro-indol-3-ylid...)
Affinity DataIC50:  2.30nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50120097((7,8-Dimethoxy-imidazo[1,5-a]quinoxalin-4-yl)-(2,6...)
Affinity DataIC50:  2.40nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50112947((6,7-Dimethoxy-imidazo[1,5-a]quinoxalin-4-yl)-(2,6...)
Affinity DataIC50:  2.40nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7691(4-[N¢-(4-Isopropyl-2-oxo-1,2-dihydro-indol-3-ylid...)
Affinity DataIC50:  2.5nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7744(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50:  2.80nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145915(CHEMBL85637 | N-[4-(2-Chloro-6-methyl-phenylamino)...)
Affinity DataIC50:  3nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50120129((2-Chloro-6-methyl-phenyl)-(6-methoxy-imidazo[1,5-...)
Affinity DataIC50:  3nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7695(4-{2-[(3Z)-2-oxo-4-(propan-2-yloxy)-2,3-dihydro-1H...)
Affinity DataIC50:  3.40nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145893((2-Chloro-6-methyl-phenyl)-(6-morpholin-4-yl-imida...)
Affinity DataIC50:  4nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145884(4-(2-Chloro-6-methyl-phenylamino)-imidazo[1,5-a]qu...)
Affinity DataIC50:  4nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7754(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50:  4.30nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7720((3Z)-2-oxo-3-[2-(4-sulfamoylphenyl)hydrazin-1-ylid...)
Affinity DataIC50:  4.5nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50370316(CHEMBL272667)
Affinity DataIC50:  4.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7748(N,N-Dimethyl-4-{[(7-oxo-6,7-dihydro-8H-[1,3]thiazo...)
Affinity DataIC50:  4.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145922(4-[N'-(4-Iodo-2-oxo-1,2-dihydro-indol-3-ylidene)-h...)
Affinity DataIC50:  4.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7749(2-hydroxy-N-[4-({[(12Z)-11-oxo-3-thia-5,10-diazatr...)
Affinity DataIC50:  4.70nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145924(CHEMBL315066 | N*4*-(2-Chloro-6-methyl-phenyl)-N*6...)
Affinity DataIC50:  5nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7747(N-Methyl-4-{[(7-oxo-6,7-dihydro-8H-[1,3]thiazolo[5...)
Affinity DataIC50:  5.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7758(N-Benzyl-4-{[(7-oxo-6,7-dihydro-8H-[1,3]thiazolo[5...)
Affinity DataIC50:  5.60nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50120106((2-Chloro-6-methyl-phenyl)-(7-morpholin-4-yl-imida...)
Affinity DataIC50:  6nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145891(CHEMBL314819 | [4-(2-Chloro-6-methyl-phenylamino)-...)
Affinity DataIC50:  6.20nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145897(CHEMBL85974 | N*4*-(2-Chloro-6-methyl-phenyl)-imid...)
Affinity DataIC50:  7nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7690(4-[2-(4-Ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene...)
Affinity DataIC50:  7.90nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50120122((2-Chloro-6-methyl-phenyl)-(7-methoxy-imidazo[1,5-...)
Affinity DataIC50:  8.70nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7724((3Z)-2-oxo-N-(pyridin-4-ylmethyl)-3-[2-(4-sulfamoy...)
Affinity DataIC50:  8.90nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50120134(CHEMBL84877 | N*4*-(2-Chloro-6-methyl-phenyl)-N*7*...)
Affinity DataIC50:  9nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50112920((2-Chloro-6-methyl-phenyl)-imidazo[1,5-a]quinoxali...)
Affinity DataIC50:  9nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50112931((2,6-Dichloro-phenyl)-imidazo[1,5-a]quinoxalin-4-y...)
Affinity DataIC50:  9nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145935(4-(2-Chloro-6-methyl-phenylamino)-5-methoxy-imidaz...)
Affinity DataIC50:  9.40nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7755(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50:  9.70nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145937(CHEMBL85976 | N*4*-(2-Chloro-6-methyl-phenyl)-N*6*...)
Affinity DataIC50:  10nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7708(4-[N -(5-Hydroxy-2-oxo-1,2-dihydro-indol-3-ylidene...)
Affinity DataIC50:  10nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145938(4-(2-Chloro-6-methyl-phenylamino)-7,8-dimethoxy-im...)
Affinity DataIC50:  10nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7706(4-[2-(5-Iodo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)...)
Affinity DataIC50:  11nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50120103(CHEMBL313466 | N-(4-(2-chloro-6-methylphenylamino)...)
Affinity DataIC50:  11nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7699(4-(N -{4-[2-(4-Hydroxyphenyl)-ethyl]-2-oxo-1,2-dih...)
Affinity DataIC50:  12nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7709(4-[N -(5-Methoxy-2-oxo-1,2-dihydro-indol-3-ylidene...)
Affinity DataIC50:  12nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7737(4-[2-(4-Chloro-5-methyl-2-oxo-1,2-dihydro-3H-indol...)
Affinity DataIC50:  13nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7696(4-[N -(2-Oxo-4-phenoxy-1,2-dihydro-indol-3-ylidene...)
Affinity DataIC50:  13nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50120121((7-Bromo-imidazo[1,5-a]quinoxalin-4-yl)-(2-chloro-...)
Affinity DataIC50:  14nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50145923((6-Bromo-imidazo[1,5-a]quinoxalin-4-yl)-(2-chloro-...)
Affinity DataIC50:  15nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50370320(CHEMBL411886)
Affinity DataIC50:  15nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50112925((2,6-Dimethyl-phenyl)-imidazo[1,5-a]quinoxalin-4-y...)
Affinity DataIC50:  16nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 112 total ) | Next | Last >>
Jump to: