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Found 10 Enz. Inhib. hit(s) with all data for entry = 50014761
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for 5-hydroxytryptamine 2 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for Beta adrenergic receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for Dopamine receptor D2 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for Dopamine receptor D1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for alpha-2 adrenergic receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for 5-hydroxytryptamine 3 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataEC50:  23nMAssay Description:Compound was tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122874(4-Amino-5-chloro-2-methoxy-N-((1S,7aS)-7a-methyl-h...)
Affinity DataEC50:  449nMAssay Description:Compound was tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataEC50:  66nMAssay Description:Tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assay of racemate mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed