Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 859
LigandChemical structure of BindingDB Monomer ID 6736BDBM6736(7-(pyrrolidin-1-ylmethyl)-1,4,14-triazaheptacyclo[...)
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6740BDBM6740(7-(piperazin-1-ylmethyl)-1,4,14-triazaheptacyclo[1...)
Affinity DataIC50: 65nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6735BDBM6735(7-(azetidin-1-ylmethyl)-1,4,14-triazaheptacyclo[16...)
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6738BDBM6738(7-(morpholin-4-ylmethyl)-1,4,14-triazaheptacyclo[1...)
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6741BDBM6741(7-(1,4-diazepan-1-ylmethyl)-1,4,14-triazaheptacycl...)
Affinity DataIC50: 79nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6737BDBM6737(7-(piperidin-1-ylmethyl)-1,4,14-triazaheptacyclo[1...)
Affinity DataIC50: 87nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6739BDBM6739(7-(thiomorpholin-4-ylmethyl)-1,4,14-triazaheptacyc...)
Affinity DataIC50: 90nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6729BDBM6729(7-bromo-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^...)
Affinity DataIC50: 90nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6720BDBM6720(1,4,14-triazaheptacyclo[16.8.1.0^{2,17}.0^{3,11}.0...)
Affinity DataIC50: 94nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6728BDBM6728(7-chloro-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0...)
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6719BDBM6719(1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^{3,11}.0...)
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6721BDBM6721(1,4,14-triazaheptacyclo[16.9.1.0^{2,17}.0^{3,11}.0...)
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6732BDBM6732(7-(pyridin-3-yl)-1,4,14-triazaheptacyclo[16.7.1.0^...)
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6734BDBM6734(7-(aminomethyl)-1,4,14-triazaheptacyclo[16.7.1.0^{...)
Affinity DataIC50: 170nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6718BDBM6718(1,4,14-triazaheptacyclo[16.6.1.0^{2,17}.0^{3,11}.0...)
Affinity DataIC50: 240nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6730BDBM6730(7-(trifluoromethyl)-1,4,14-triazaheptacyclo[16.7.1...)
Affinity DataIC50: 290nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6727BDBM6727(7-fluoro-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0...)
Affinity DataIC50: 420nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6733BDBM6733(7-(pyridin-4-yl)-1,4,14-triazaheptacyclo[16.7.1.0^...)
Affinity DataIC50: 590nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6719BDBM6719(1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^{3,11}.0...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6720BDBM6720(1,4,14-triazaheptacyclo[16.8.1.0^{2,17}.0^{3,11}.0...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6729BDBM6729(7-bromo-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6723BDBM6723(7,8-difluoro-1,4,14-triazaheptacyclo[16.7.1.0^{2,1...)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6724BDBM6724(8-fluoro-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0...)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6725BDBM6725(8-bromo-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^...)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6726BDBM6726(methyl 13,15-dioxo-1,4,14-triazaheptacyclo[16.7.1....)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6718BDBM6718(1,4,14-triazaheptacyclo[16.6.1.0^{2,17}.0^{3,11}.0...)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6721BDBM6721(1,4,14-triazaheptacyclo[16.9.1.0^{2,17}.0^{3,11}.0...)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6727BDBM6727(7-fluoro-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0...)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6731BDBM6731(methyl 13,15-dioxo-1,4,14-triazaheptacyclo[16.7.1....)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6728BDBM6728(7-chloro-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0...)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6730BDBM6730(7-(trifluoromethyl)-1,4,14-triazaheptacyclo[16.7.1...)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 6722BDBM6722(9-fluoro-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0...)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed