Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50042016
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Membrane Research Group of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50305083(Ko143 | Ko-143 | 3-((3S,6S)-6-Isobutyl-9-methoxy-1...)
Affinity DataIC50: 5nMAssay Description:TP_TRANSPORTER: efflux of Hoechst33342 in BCRP-expressing Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Membrane Research Group of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4566(N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...)
Affinity DataIC50: 200nMAssay Description:TP_TRANSPORTER: efflux of Hoechst33342 in BCRP-expressing Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Membrane Research Group of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 400nMAssay Description:TP_TRANSPORTER: efflux of Hoechst33342 in BCRP-expressing Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Membrane Research Group of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 500nMAssay Description:TP_TRANSPORTER: inhibition of ATPase activity in BCRP-expressing Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Membrane Research Group of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 900nMAssay Description:TP_TRANSPORTER: efflux of Hoechst33342 in BCRP-expressing Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Membrane Research Group of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50338982((R)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3...)
Affinity DataIC50: 5.00E+4nMAssay Description:TP_TRANSPORTER: efflux of Hoechst33342 in BCRP-expressing Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed