Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50037323
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150333(CHEMBL183510 | N-[3-(Benzyl-{4-[4-((1R,3S)-4-hydro...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150340((3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150336((4R,6S)-4-Hydroxy-6-({[4-((8S,11R,13S,14S,17S)-17-...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(CHEMBL182610 | N-{3-[Benzyl-(4-phenoxy-benzyl)-ami...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150336((4R,6S)-4-Hydroxy-6-({[4-((8S,11R,13S,14S,17S)-17-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150332((S)-3,5-Dihydroxy-6-[4-((8S,11R,13S,14S,17S)-17-hy...)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150335((2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methane...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50:  18nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150338(CHEMBL181604 | N-{3-[(2,4-Difluoro-benzyl)-(4-phen...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150336((4R,6S)-4-Hydroxy-6-({[4-((8S,11R,13S,14S,17S)-17-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150334(CHEMBL182058 | N-[3-((2,4-Difluoro-benzyl)-{4-[3-(...)
Affinity DataIC50:  25nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150339((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...)
Affinity DataIC50:  37nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150332((S)-3,5-Dihydroxy-6-[4-((8S,11R,13S,14S,17S)-17-hy...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150339((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...)
Affinity DataIC50:  76nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50:  130nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150336((4R,6S)-4-Hydroxy-6-({[4-((8S,11R,13S,14S,17S)-17-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150339((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150339((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...)
Affinity DataIC50:  220nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(CHEMBL182610 | N-{3-[Benzyl-(4-phenoxy-benzyl)-ami...)
Affinity DataIC50:  240nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  270nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150340((3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2...)
Affinity DataIC50:  300nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150338(CHEMBL181604 | N-{3-[(2,4-Difluoro-benzyl)-(4-phen...)
Affinity DataIC50:  385nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150333(CHEMBL183510 | N-[3-(Benzyl-{4-[4-((1R,3S)-4-hydro...)
Affinity DataIC50:  440nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150332((S)-3,5-Dihydroxy-6-[4-((8S,11R,13S,14S,17S)-17-hy...)
Affinity DataIC50:  560nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150334(CHEMBL182058 | N-[3-((2,4-Difluoro-benzyl)-{4-[3-(...)
Affinity DataIC50:  670nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150335((2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methane...)
Affinity DataIC50:  760nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150332((S)-3,5-Dihydroxy-6-[4-((8S,11R,13S,14S,17S)-17-hy...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(CHEMBL182610 | N-{3-[Benzyl-(4-phenoxy-benzyl)-ami...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150338(CHEMBL181604 | N-{3-[(2,4-Difluoro-benzyl)-(4-phen...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150335((2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methane...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150333(CHEMBL183510 | N-[3-(Benzyl-{4-[4-((1R,3S)-4-hydro...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150340((3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150334(CHEMBL182058 | N-[3-((2,4-Difluoro-benzyl)-{4-[3-(...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed