Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50015042
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150685(((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  0.870nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150676(((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine | (R)-8...)
Affinity DataKi:  1.23nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150678(CHEMBL186758 | [(R)-8-(4-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  1.31nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150677(CHEMBL188176 | [(S)-5-(4-Methoxy-phenyl)-1,2,3,4-t...)
Affinity DataKi:  1.49nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150680(CHEMBL184535 | [(S)-5-(2-Methoxy-phenyl)-1,2,3,4-t...)
Affinity DataKi:  1.73nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150681(4-(4-Chloro-phenoxy)-1-{2-[(R)-1-(3H-indene-5-sulf...)
Affinity DataKi:  1.99nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50125260(2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...)
Affinity DataKi:  2.24nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  2.55nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  2.55nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150679(CHEMBL186316 | [(R)-8-(2-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150676(((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine | (R)-8...)
Affinity DataKi:  2.92nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150685(((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  3.38nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50098549((6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Affinity DataKi:  3.79nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150684((R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-...)
Affinity DataKi:  5.29nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150686(CHEMBL182792 | [(R)-8-(2,6-Dimethoxy-phenyl)-chrom...)
Affinity DataKi:  6.44nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150682(2a-[4-(6,7-Dihydro-4H-thieno[3,2-c]pyridin-5-yl)-b...)
Affinity DataKi:  6.46nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150674(CHEMBL361875 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  7.90nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150674(CHEMBL361875 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  7.90nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150679(CHEMBL186316 | [(R)-8-(2-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  10.3nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150680(CHEMBL184535 | [(S)-5-(2-Methoxy-phenyl)-1,2,3,4-t...)
Affinity DataKi:  11.7nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150677(CHEMBL188176 | [(S)-5-(4-Methoxy-phenyl)-1,2,3,4-t...)
Affinity DataKi:  12.4nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150678(CHEMBL186758 | [(R)-8-(4-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  12.6nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150675((S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  78.7nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150676(((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine | (R)-8...)
Affinity DataKi:  106nMAssay Description:Inhibition of [3H]-Raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50098549((6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Affinity DataKi:  142nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150686(CHEMBL182792 | [(R)-8-(2,6-Dimethoxy-phenyl)-chrom...)
Affinity DataKi:  174nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50125260(2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...)
Affinity DataKi:  234nMAssay Description:Inhibition of [3H]-Raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  241nMAssay Description:Inhibition of [3H]-Raclopride binding to human dopamine D2A receptor expressed in Ltk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  241nMAssay Description:Inhibition of [3H]-Raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150674(CHEMBL361875 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  347nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150674(CHEMBL361875 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  347nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to human 5-HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150683(CHEMBL361287 | [(S)-8-(2-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  364nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50125260(2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...)
Affinity DataKi:  479nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50098549((6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Affinity DataKi:  498nMAssay Description:Inhibition of [3H]-Raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150679(CHEMBL186316 | [(R)-8-(2-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  512nMAssay Description:Inhibition of [3H]-Raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150682(2a-[4-(6,7-Dihydro-4H-thieno[3,2-c]pyridin-5-yl)-b...)
Affinity DataKi:  513nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150681(4-(4-Chloro-phenoxy)-1-{2-[(R)-1-(3H-indene-5-sulf...)
Affinity DataKi:  562nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150683(CHEMBL361287 | [(S)-8-(2-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  680nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150678(CHEMBL186758 | [(R)-8-(4-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  741nMAssay Description:Inhibition of [3H]-Raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150674(CHEMBL361875 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi: >900nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150675((S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-na...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150684((R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150674(CHEMBL361875 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  1.21E+3nMAssay Description:Inhibition of [3H]-Raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150674(CHEMBL361875 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  1.21E+3nMAssay Description:Inhibition of [3H]-Raclopride binding to human dopamine D2A receptor expressed in Ltk cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to human 5-HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150683(CHEMBL361287 | [(S)-8-(2-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  2.11E+3nMAssay Description:Inhibition of [3H]-Raclopride binding to Dopamine receptor D2A in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]- GR-65630 binding to rabbit ileum muscularis 5-HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]- GR-113808 binding to guinea pig striatum 5-HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed