Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 1160
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9454(7-(benzyloxy)-3-phenyl-2-[(pyridin-4-ylmethyl)sulf...)
Affinity DataKi:  220nM ΔG°:  -39.5kJ/mole IC50: 210nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9459(7-hydroxy-3-(4-methoxyphenyl)-2-[(pyridin-4-ylmeth...)
Affinity DataKi:  260nM ΔG°:  -39.1kJ/mole IC50: 220nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9458(CHEMBL185950 | 7-hydroxy-3-(4-hydroxyphenyl)-2-[(p...)
Affinity DataKi:  310nM ΔG°:  -38.6kJ/mole IC50: 280nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9455(CHEMBL186079 | 3-(4-Methoxyphenyl)-7-(phenylmethox...)
Affinity DataIC50: 530nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9456(7-hydroxy-3-phenyl-2-[(pyridin-4-ylmethyl)sulfanyl...)
Affinity DataIC50: 610nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9449(CHEMBL185809 | 7-methoxy-3-phenyl-2-[(pyridin-4-yl...)
Affinity DataKi:  900nM ΔG°:  -35.9kJ/mole IC50: 1.60E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9452(CHEMBL184051 | 7-methoxy-3-(4-methylphenyl)-2-[(py...)
Affinity DataKi:  1.16E+3nM ΔG°:  -35.2kJ/mole IC50: 3.00E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9453(7-methoxy-3-(4-methoxyphenyl)-2-[(pyridin-4-ylmeth...)
Affinity DataKi:  1.69E+3nM ΔG°:  -34.3kJ/mole IC50: 3.10E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9457(CHEMBL364326 | 7-Hydroxy-3-phenyl-2-[(3-pyridylmet...)
Affinity DataIC50: 3.60E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9450(7-methoxy-3-phenyl-2-[(pyridin-3-ylmethyl)sulfanyl...)
Affinity DataIC50: 9.20E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataKi:  1.20E+4nM ΔG°:  -29.2kJ/mole IC50: 3.40E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9445(3-(4-Methoxyphenyl)-7-(phenylmethoxy)-2-[(propen-3...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9446(3-(4-Methoxyphenyl)-7-(phenylmethoxy)-2-[(phenylme...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9447(7-Methoxy-3-phenyl-2-[(propen-3-yl)thio]-4H-1-benz...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9448(2-(benzylsulfanyl)-7-methoxy-3-phenyl-4H-chromen-4...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9451(7-methoxy-3-phenyl-2-[(pyridin-2-ylmethyl)sulfanyl...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed