Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50015149
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152188((4-Chloro-benzyl)-[3-(6-dimethylamino-4-methyl-pyr...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50071235(Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-2,5-dim...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152164([3-(6-Dimethylamino-2-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152183([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152179([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152178([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152176((3,4-Dichloro-benzyl)-[3-(6-dimethylamino-4-methyl...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152169(Cyclopropylmethyl-[3-(6-dimethylamino-4-methyl-pyr...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152173(Butyl-[3-(6-dimethylamino-4-methyl-pyridin-3-yl)-2...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152170(Benzyl-butyl-[3-(6-dimethylamino-4-methyl-pyridin-...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152160([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50148889([3-(2,4-Dimethoxy-phenyl)-2,5-dimethyl-3H-pyrazolo...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152162(CHEMBL2165204 | CHEMBL188844 | [3-(6-Dimethylamino...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152185(Dibutyl-[3-(6-dimethylamino-4-methyl-pyridin-3-yl)...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152186([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152172(Benzyl-[3-(6-dimethylamino-4-methyl-pyridin-3-yl)-...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152177([3-(6-Dimethylamino-2,4-dimethyl-pyridin-3-yl)-2,5...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152163([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-6-fluor...)
Affinity DataKi:  5.60nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152180((1-Benzyl-2-methoxy-ethyl)-[3-(6-dimethylamino-4-m...)
Affinity DataKi:  6.5nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152159([3-(4,6-Dimethyl-pyridin-3-yl)-2,5-dimethyl-pyrazo...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152182([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149669([2,5-Dimethyl-3-(3-methyl-5-nitro-pyridin-2-yl)-py...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152165([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  9.40nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149672([3-(5-Dimethylamino-3-methyl-pyridin-2-yl)-2,5-dim...)
Affinity DataKi:  10nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152166(Benzyl-[3-(6-dimethylamino-4-methyl-pyridin-3-yl)-...)
Affinity DataKi:  11nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152184([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  13nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152187([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  15nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152167([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  17nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152161([3-(6-Dimethylamino-2,4-dimethyl-pyridin-3-yl)-5-m...)
Affinity DataKi:  20nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152168([2,5-Dimethyl-3-(6-methyl-pyridin-3-yl)-pyrazolo[1...)
Affinity DataKi:  21nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152181([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  24nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50071235(Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-2,5-dim...)
Affinity DataIC50: 29nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152174([6-Chloro-3-(6-dimethylamino-4-methyl-pyridin-3-yl...)
Affinity DataKi:  39nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152177([3-(6-Dimethylamino-2,4-dimethyl-pyridin-3-yl)-2,5...)
Affinity DataIC50: 40nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152163([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-6-fluor...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50148889([3-(2,4-Dimethoxy-phenyl)-2,5-dimethyl-3H-pyrazolo...)
Affinity DataIC50: 76nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149653([3-(5-Amino-3-methyl-pyridin-2-yl)-2,5-dimethyl-py...)
Affinity DataKi:  85nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152162(CHEMBL2165204 | CHEMBL188844 | [3-(6-Dimethylamino...)
Affinity DataIC50: 110nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149672([3-(5-Dimethylamino-3-methyl-pyridin-2-yl)-2,5-dim...)
Affinity DataIC50: 160nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149669([2,5-Dimethyl-3-(3-methyl-5-nitro-pyridin-2-yl)-py...)
Affinity DataIC50: 180nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152164([3-(6-Dimethylamino-2-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataIC50: 190nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152171([6-Bromo-3-(6-dimethylamino-4-methyl-pyridin-3-yl)...)
Affinity DataKi:  240nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152175([3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dim...)
Affinity DataKi:  260nMAssay Description:Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed