Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50015156
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152303(N-((S)-1-benzylpyrrolidin-3-yl)-3-(thiophen-2-yl)b...)
Affinity DataKi:  1.5nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152298(N-((S)-1-Benzyl-pyrrolidin-3-yl)-3-thiophen-3-yl-b...)
Affinity DataKi:  2nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152296(N-((S)-1-Benzyl-pyrrolidin-3-yl)-4-thiophen-3-yl-b...)
Affinity DataKi:  2nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152306(N-(1-Benzyl-pyrrolidin-3-yl)-4-thiophen-3-yl-benza...)
Affinity DataKi:  2nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152297(N-(1-Benzyl-pyrrolidin-3-yl)-4-thiophen-2-yl-benza...)
Affinity DataKi:  3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152305(Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Affinity DataKi:  3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152314((S)-N-(1-benzylpyrrolidin-3-yl)-4-(thiophen-2-yl)b...)
Affinity DataKi:  3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152302(N-((R)-1-Benzyl-pyrrolidin-3-yl)-3-thiophen-3-yl-b...)
Affinity DataKi:  3.40nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152309(Biphenyl-3-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Affinity DataKi:  4nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152311(4''-Chloro-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  5nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152310(4''-Fluoro-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  8nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152313(4''-Trifluoromethyl-biphenyl-4-carboxylic acid (1-...)
Affinity DataKi:  17nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152312(3''-Fluoro-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  17nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152308(4''-Methylsulfanyl-biphenyl-4-carboxylic acid (1-b...)
Affinity DataKi:  17nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152301(N-((R)-1-Benzyl-pyrrolidin-3-yl)-4-thiophen-3-yl-b...)
Affinity DataKi:  18nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152307(N-((R)-1-Benzyl-pyrrolidin-3-yl)-4-thiophen-2-yl-b...)
Affinity DataKi:  24nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152304(3''-Amino-biphenyl-4-carboxylic acid (1-benzyl-pyr...)
Affinity DataKi:  24nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152299(2''-Formyl-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  36nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152303(N-((S)-1-benzylpyrrolidin-3-yl)-3-(thiophen-2-yl)b...)
Affinity DataKi:  60nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152298(N-((S)-1-Benzyl-pyrrolidin-3-yl)-3-thiophen-3-yl-b...)
Affinity DataKi:  70nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152300(4''-Formyl-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  70nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152302(N-((R)-1-Benzyl-pyrrolidin-3-yl)-3-thiophen-3-yl-b...)
Affinity DataKi:  94nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152310(4''-Fluoro-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  120nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152309(Biphenyl-3-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Affinity DataKi:  150nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152305(Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Affinity DataKi:  600nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152297(N-(1-Benzyl-pyrrolidin-3-yl)-4-thiophen-2-yl-benza...)
Affinity DataKi:  840nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152301(N-((R)-1-Benzyl-pyrrolidin-3-yl)-4-thiophen-3-yl-b...)
Affinity DataKi:  900nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152314((S)-N-(1-benzylpyrrolidin-3-yl)-4-(thiophen-2-yl)b...)
Affinity DataKi:  980nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152296(N-((S)-1-Benzyl-pyrrolidin-3-yl)-4-thiophen-3-yl-b...)
Affinity DataKi:  1.00E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152306(N-(1-Benzyl-pyrrolidin-3-yl)-4-thiophen-3-yl-benza...)
Affinity DataKi:  1.20E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152307(N-((R)-1-Benzyl-pyrrolidin-3-yl)-4-thiophen-2-yl-b...)
Affinity DataKi:  1.50E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152305(Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration required to reverse the dopamine inhibition of forskolin-stimulated adenyl cyclase activity in CHO cells stably expressing h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152311(4''-Chloro-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  2.60E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152299(2''-Formyl-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  3.10E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152300(4''-Formyl-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  3.70E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152308(4''-Methylsulfanyl-biphenyl-4-carboxylic acid (1-b...)
Affinity DataKi:  4.00E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152312(3''-Fluoro-biphenyl-4-carboxylic acid (1-benzyl-py...)
Affinity DataKi:  4.00E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152304(3''-Amino-biphenyl-4-carboxylic acid (1-benzyl-pyr...)
Affinity DataKi:  5.00E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152313(4''-Trifluoromethyl-biphenyl-4-carboxylic acid (1-...)
Affinity DataKi:  8.00E+3nMAssay Description:Ability to displace [3H]spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed