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Found 60 Enz. Inhib. hit(s) with all data for entry = 50037465
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  10.6nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154243(4-[(6-Benzhydryl-piperidin-3-ylamino)-methyl]-benz...)
Affinity DataIC50:  11.2nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098392((2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidi...)
Affinity DataIC50:  19.7nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50103818((6-Benzhydryl-piperidin-3-yl)-(4-fluoro-benzyl)-am...)
Affinity DataIC50:  33.8nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154228((6-Benzhydryl-piperidin-3-yl)-(4-methoxy-benzyl)-a...)
Affinity DataIC50:  47.5nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154231(8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicycl...)
Affinity DataIC50:  68.9nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154232(8-Benzhydryl-4-(4-fluoro-phenyl)-1,4-diaza-bicyclo...)
Affinity DataIC50:  81.2nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154233(4-(8-Benzhydryl-1,4-diaza-bicyclo[3.3.1]non-4-yl)-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  132nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098392((2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidi...)
Affinity DataIC50:  137nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154235(8-Benzhydryl-4-(3,4-dichloro-phenyl)-1,4-diaza-bic...)
Affinity DataIC50:  210nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154244(8-Benzhydryl-4-(4-ethoxy-phenyl)-1,4-diaza-bicyclo...)
Affinity DataIC50:  215nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154239((6-Benzhydryl-1-methyl-piperidin-3-yl)-(4-fluoro-b...)
Affinity DataIC50:  225nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  266nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154230(8-Benzhydryl-4-naphthalen-2-yl-1,4-diaza-bicyclo[3...)
Affinity DataIC50:  308nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154237(CHEMBL187429 | N-[4-(8-Benzhydryl-1,4-diaza-bicycl...)
Affinity DataIC50:  371nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154243(4-[(6-Benzhydryl-piperidin-3-ylamino)-methyl]-benz...)
Affinity DataIC50:  434nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  496nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154241(8-Benzhydryl-4-[2-(4-fluoro-phenyl)-ethyl]-1,4-dia...)
Affinity DataIC50:  565nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154238(4-(8-Benzhydryl-1,4-diaza-bicyclo[3.3.1]non-4-yl)-...)
Affinity DataIC50:  581nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154230(8-Benzhydryl-4-naphthalen-2-yl-1,4-diaza-bicyclo[3...)
Affinity DataIC50:  672nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  737nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154242(8-Benzhydryl-4-naphthalen-1-yl-1,4-diaza-bicyclo[3...)
Affinity DataIC50:  958nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154228((6-Benzhydryl-piperidin-3-yl)-(4-methoxy-benzyl)-a...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154242(8-Benzhydryl-4-naphthalen-1-yl-1,4-diaza-bicyclo[3...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154228((6-Benzhydryl-piperidin-3-yl)-(4-methoxy-benzyl)-a...)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098392((2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidi...)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154236(CHEMBL187142 | [6-Benzhydryl-1-(4-fluoro-benzyl)-p...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50103818((6-Benzhydryl-piperidin-3-yl)-(4-fluoro-benzyl)-am...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154229(4-(8-Benzhydryl-1,4-diaza-bicyclo[3.3.1]non-4-yl)-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50103818((6-Benzhydryl-piperidin-3-yl)-(4-fluoro-benzyl)-am...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154243(4-[(6-Benzhydryl-piperidin-3-ylamino)-methyl]-benz...)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154242(8-Benzhydryl-4-naphthalen-1-yl-1,4-diaza-bicyclo[3...)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154235(8-Benzhydryl-4-(3,4-dichloro-phenyl)-1,4-diaza-bic...)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154239((6-Benzhydryl-1-methyl-piperidin-3-yl)-(4-fluoro-b...)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154241(8-Benzhydryl-4-[2-(4-fluoro-phenyl)-ethyl]-1,4-dia...)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154237(CHEMBL187429 | N-[4-(8-Benzhydryl-1,4-diaza-bicycl...)
Affinity DataIC50:  3.48E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154233(4-(8-Benzhydryl-1,4-diaza-bicyclo[3.3.1]non-4-yl)-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154237(CHEMBL187429 | N-[4-(8-Benzhydryl-1,4-diaza-bicycl...)
Affinity DataIC50:  4.13E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154240(8-Benzhydryl-4-methyl-1,4-diaza-bicyclo[3.3.1]nona...)
Affinity DataIC50:  4.71E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154230(8-Benzhydryl-4-naphthalen-2-yl-1,4-diaza-bicyclo[3...)
Affinity DataIC50:  5.79E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154231(8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicycl...)
Affinity DataIC50:  5.83E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154239((6-Benzhydryl-1-methyl-piperidin-3-yl)-(4-fluoro-b...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154235(8-Benzhydryl-4-(3,4-dichloro-phenyl)-1,4-diaza-bic...)
Affinity DataIC50:  8.03E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154238(4-(8-Benzhydryl-1,4-diaza-bicyclo[3.3.1]non-4-yl)-...)
Affinity DataIC50:  8.32E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154232(8-Benzhydryl-4-(4-fluoro-phenyl)-1,4-diaza-bicyclo...)
Affinity DataIC50:  8.86E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154231(8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicycl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154241(8-Benzhydryl-4-[2-(4-fluoro-phenyl)-ethyl]-1,4-dia...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154244(8-Benzhydryl-4-(4-ethoxy-phenyl)-1,4-diaza-bicyclo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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