Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50015411
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155778(1-[4-((S)-3,10-Dibromo-8-chloro-11H-benzo[5,6]cycl...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155775(4-{2-[4-((S)-3,10-Dibromo-8-chloro-11H-benzo[5,6]c...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155776((S)-3,10-Dibromo-8-chloro-11-(1-methanesulfonyl-pi...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155777(4-{2-[4-((R)-3,10-Dibromo-8-chloro-11H-benzo[5,6]c...)
Affinity DataIC50:  16nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of K-Ras transformed NIH3T3 cell proliferationMore data for this Ligand-Target Pair