Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50048896
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009568BDBM50009568((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...)
Affinity DataIC50: 640nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005480BDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230627BDBM50230627(CHEMBL10519)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009568BDBM50009568((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...)
Affinity DataIC50: 1.40E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005478BDBM50005478(CHEMBL10557 | 2-methoxy-5-(3,4,5-trimethoxypheneth...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230630BDBM50230630(CHEMBL10144)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230635BDBM50230635(CHEMBL10642)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230622BDBM50230622(CHEMBL274212)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212289BDBM50212289(CHEMBL10121)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230626BDBM50230626(CHEMBL10703)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005480BDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230627BDBM50230627(CHEMBL10519)
Affinity DataIC50: 2.60E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230631BDBM50230631(CHEMBL275976)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212303BDBM50212303(CHEMBL10215)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005478BDBM50005478(CHEMBL10557 | 2-methoxy-5-(3,4,5-trimethoxypheneth...)
Affinity DataIC50: 3.50E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230628BDBM50230628(CHEMBL273261)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230625BDBM50230625(CHEMBL10686)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230633BDBM50230633(CHEMBL10559)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212300BDBM50212300(CHEMBL10127)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230629BDBM50230629(CHEMBL10405)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230632BDBM50230632(CHEMBL10185)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212289BDBM50212289(CHEMBL10121)
Affinity DataIC50: 7.70E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230624BDBM50230624(CHEMBL269215)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212303BDBM50212303(CHEMBL10215)
Affinity DataIC50: 1.10E+4nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212300BDBM50212300(CHEMBL10127)
Affinity DataIC50: 3.00E+4nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230623BDBM50230623(CHEMBL10255)
Affinity DataIC50: 4.00E+4nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230623BDBM50230623(CHEMBL10255)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230634BDBM50230634(CHEMBL10653)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details Article
PubMed