Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50015466
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156313BDBM50156313(4-[3-(3-{2-[1-(2-Methoxy-phenyl)-piperidin-4-ylami...)
Affinity DataKi:  1.90nMAssay Description:Antagonist activity towards Neuropeptide Y receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156319BDBM50156319(2,6-Dimethyl-4-(3-{3-[2-(1-phenyl-piperidin-4-ylam...)
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156313BDBM50156313(4-[3-(3-{2-[1-(2-Methoxy-phenyl)-piperidin-4-ylami...)
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156328BDBM50156328(2,6-Dimethyl-4-[3-(3-{2-[1-(2-nitro-phenyl)-piperi...)
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156323BDBM50156323(N-arylpiperazine derivative | CHEMBL189412)
Affinity DataIC50: 3nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156317BDBM50156317(N-arylpiperazine derivative | CHEMBL187925)
Affinity DataIC50: 3nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156326BDBM50156326(4-[3-(3-{2-[1-(2-Cyano-phenyl)-piperidin-4-ylamino...)
Affinity DataIC50: 3nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156311BDBM50156311(N-arylpiperazine derivative | CHEMBL187620)
Affinity DataKi:  3.60nMAssay Description:Antagonist activity towards Neuropeptide Y receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156318BDBM50156318(N-arylpiperazine derivative | CHEMBL361273)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156316BDBM50156316(N-arylpiperazine derivative | CHEMBL188576)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156331BDBM50156331(2,6-Dimethyl-4-(3-{3-[2-(1-o-tolyl-piperidin-4-yla...)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156311BDBM50156311(N-arylpiperazine derivative | CHEMBL187620)
Affinity DataIC50: 4nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156322BDBM50156322(2,6-Dimethyl-4-[3-(3-{2-[1-(2-methylsulfanyl-pheny...)
Affinity DataIC50: 5nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156314BDBM50156314(N-arylpiperazine derivative | CHEMBL364380)
Affinity DataIC50: 5nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156312BDBM50156312(4-[3-(3-{2-[1-(2-Hydroxy-phenyl)-piperidin-4-ylami...)
Affinity DataIC50: 6nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156321BDBM50156321(N-arylpiperazine derivative | CHEMBL187490)
Affinity DataIC50: 8nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156315BDBM50156315(4-[3-(3-{2-[1-(3-Chloro-phenyl)-piperidin-4-ylamin...)
Affinity DataIC50: 8nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156325BDBM50156325(N-arylpiperazine derivative | CHEMBL188790)
Affinity DataIC50: 10nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109185BDBM50109185(BMS-189323 | 4-[3-(3-{3-[4-(2-Methoxy-phenyl)-pipe...)
Affinity DataIC50: 12nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156327BDBM50156327(N-arylpiperazine derivative | CHEMBL189036)
Affinity DataIC50: 14nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156324BDBM50156324(2,6-Dimethyl-4-[3-(3-{2-[1-(2-trifluoromethoxy-phe...)
Affinity DataIC50: 25nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156329BDBM50156329(N-arylpiperazine derivative | CHEMBL187782)
Affinity DataIC50: 28nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156320BDBM50156320(2,6-Dimethyl-4-[3-(3-{2-[1-(2-trifluoromethyl-phen...)
Affinity DataIC50: 31nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156330BDBM50156330(BMS-245782 | N-arylpiperazine derivative | CHEMBL1...)
Affinity DataIC50: 39nMAssay Description:Inhibition of binding of [125I]PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed