Compile Data Set for Download or QSAR
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Found 16 Enz. Inhib. hit(s) with all data for entry = 50015486
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2939(4-(2-cyclopropylethynyl)-5-fluoro-4-(trifluorometh...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2942(5-fluoro-4-(3-methylbut-1-yn-1-yl)-4-(trifluoromet...)
Affinity DataIC50:  102nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2940(4-(but-1-yn-1-yl)-5-fluoro-4-(trifluoromethyl)-2,4...)
Affinity DataIC50:  127nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2941(5-fluoro-4-(pent-1-yn-1-yl)-4-(trifluoromethyl)-2,...)
Affinity DataIC50:  156nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2946(4-(3-methylbut-1-yn-1-yl)-6-nitro-4-(trifluorometh...)
Affinity DataIC50:  199nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2943(4-(2-cyclopropylethynyl)-6-nitro-4-(trifluoromethy...)
Affinity DataIC50:  209nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2944(4-(but-1-yn-1-yl)-6-nitro-4-(trifluoromethyl)-2,4-...)
Affinity DataIC50:  276nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2945(6-nitro-4-(pent-1-yn-1-yl)-4-(trifluoromethyl)-2,4...)
Affinity DataIC50:  304nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2952(6-(methylamino)-4-(3-methylbut-1-yn-1-yl)-4-(trifl...)
Affinity DataIC50:  473nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2951(4-(2-cyclopropylethynyl)-6-(methylamino)-4-(triflu...)
Affinity DataIC50:  608nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2947(6-amino-4-(2-cyclopropylethynyl)-4-(trifluoromethy...)
Affinity DataIC50:  802nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2950(6-amino-4-(3-methylbut-1-yn-1-yl)-4-(trifluorometh...)
Affinity DataIC50:  896nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2949(6-amino-4-(pent-1-yn-1-yl)-4-(trifluoromethyl)-2,4...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2948(6-amino-4-(but-1-yn-1-yl)-4-(trifluoromethyl)-2,4-...)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2953(Benzoxazinone deriv. 8a | CHEMBL111492 | N-[4-(2-c...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
S.G.S.I.T.S.

Curated by ChEMBL
LigandPNGBDBM2954(Benzoxazinone deriv. 8b | CHEMBL111598 | N-[4-(3-m...)
Affinity DataIC50: <2.00E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed