Compile Data Set for Download or QSAR
Report error Found 103 Enz. Inhib. hit(s) with all data for entry = 50037534
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159192BDBM50159192(4-Iodo-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34145BDBM34145(pyrrolidinylindole, (R)-5b)
Affinity DataKi:  0.400nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159187BDBM50159187(3-Chloro-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159176BDBM50159176(2-Bromo-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of 5-HT stimulated cAMP production in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159209BDBM50159209(3,5-Dimethyl-isoxazole-4-sulfonic acid [3-((R)-1-m...)
Affinity DataEC50:  0.800nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159195BDBM50159195(Naphthalene-2-sulfonic acid [3-((R)-1-methyl-pyrro...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159194BDBM50159194(4-Fluoro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159196BDBM50159196(3-Chloro-N-(3-(S)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataEC50:  1nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159178BDBM50159178(4-Methyl-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159199BDBM50159199(4-Isopropyl-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-in...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159202BDBM50159202(N-[3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159209BDBM50159209(3,5-Dimethyl-isoxazole-4-sulfonic acid [3-((R)-1-m...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159195BDBM50159195(Naphthalene-2-sulfonic acid [3-((R)-1-methyl-pyrro...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159182BDBM50159182(4-Isopropyl-N-[3-((S)-1-methyl-pyrrolidin-2-ylmeth...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159190BDBM50159190(N-[3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159201BDBM50159201(2-Fluoro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159188BDBM50159188(4-Methoxy-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159207BDBM50159207(N-[3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159180BDBM50159180(2-Chloro-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159208BDBM50159208(3,4-Dichloro-N-[3-((S)-1-methyl-pyrrolidin-2-ylmet...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159203BDBM50159203(4-Iodo-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159194BDBM50159194(4-Fluoro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataEC50:  1.10nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159180BDBM50159180(2-Chloro-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataEC50:  1.10nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159204BDBM50159204(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 5-HT stimulated cAMP production in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159175BDBM50159175(2-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataEC50:  1.30nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159178BDBM50159178(4-Methyl-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataEC50:  1.30nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159201BDBM50159201(2-Fluoro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataEC50:  1.30nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159181BDBM50159181(N-(3-(R)-1-Pyrrolidin-2-ylmethyl-1H-indol-5-yl)-be...)
Affinity DataEC50:  1.40nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159197BDBM50159197(4-Bromo-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of 5-HT stimulated cAMP production in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159187BDBM50159187(3-Chloro-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataEC50:  1.60nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159204BDBM50159204(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159196BDBM50159196(3-Chloro-N-(3-(S)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159188BDBM50159188(4-Methoxy-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl...)
Affinity DataEC50:  2.20nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159187BDBM50159187(3-Chloro-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to human 5-hydroxytryptamine 1F receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159192BDBM50159192(4-Iodo-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataEC50:  2.70nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159190BDBM50159190(N-[3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Affinity DataEC50:  2.90nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159182BDBM50159182(4-Isopropyl-N-[3-((S)-1-methyl-pyrrolidin-2-ylmeth...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159198BDBM50159198(3,4-Dichloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-i...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159200BDBM50159200(4-Bromo-N-(3-(S)-1-pyrrolidin-2-ylmethyl-1H-indol-...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159175BDBM50159175(2-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159210BDBM50159210(4-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159202BDBM50159202(N-[3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Affinity DataEC50:  3.20nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159181BDBM50159181(N-(3-(R)-1-Pyrrolidin-2-ylmethyl-1H-indol-5-yl)-be...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159179BDBM50159179(4-Methyl-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159189BDBM50159189(2-Fluoro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159184BDBM50159184(N-(3-(R)-1-Pyrrolidin-2-ylmethyl-1H-indol-5-yl)-3-...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159185BDBM50159185(4-Fluoro-N-(3-(S)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159206BDBM50159206(N-(3-(R)-1-Pyrrolidin-2-ylmethyl-1H-indol-5-yl)-4-...)
Affinity DataEC50:  4.20nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159187BDBM50159187(3-Chloro-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34145BDBM34145(pyrrolidinylindole, (R)-5b)
Affinity DataEC50:  4.5nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 103 total ) | Next | Last >>
Jump to: