Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50015757
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM18372(CHEMBL1496 | Ros | (3R,5S,6E)-7-[4-(4-fluorophenyl...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM50139181(2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(...)
Affinity DataKi:  2.60nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM18372(CHEMBL1496 | Ros | (3R,5S,6E)-7-[4-(4-fluorophenyl...)
Affinity DataIC50: 5.40nMAssay Description:Inhibitory concentration against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM50139181(2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(...)
Affinity DataIC50: 11.2nMAssay Description:Inhibitory concentration against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM50160720(3-hydroxy-3-methylpentanedioic acid | 3-hydroxy-3-...)
Affinity DataKi:  23.5nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM50160720(3-hydroxy-3-methylpentanedioic acid | 3-hydroxy-3-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM50139181(2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(...)
Affinity DataKi:  6.80E+4nMAssay Description:Inhibitory constant against HMG-CoA reductase with alpha asaroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM18372(CHEMBL1496 | Ros | (3R,5S,6E)-7-[4-(4-fluorophenyl...)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibitory constant against HMG-CoA reductase with alpha asaroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed