Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50015773
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50093965(CHEMBL86324 | N-Methyl-N-((S)-1-phenyl-2-pyrrolidi...)
Affinity DataKi:  0.0580nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160834(CHEMBL183248 | N-[(S)-1-(3-Amino-phenyl)-2-pyrroli...)
Affinity DataKi:  0.310nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160840(CHEMBL365486 | N-[(S)-1-(3-Methanesulfonylamino-ph...)
Affinity DataKi:  0.360nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160832(CHEMBL181279 | N-[1-(3-Hydroxy-phenyl)-2-pyrrolidi...)
Affinity DataKi:  0.440nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160842(CHEMBL362248 | N-[(S)-1-(3-aminosulfonylamino-phen...)
Affinity DataKi:  0.480nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160836(CHEMBL180803 | N-[1-(3-Methoxy-phenyl)-2-pyrrolidi...)
Affinity DataKi:  0.530nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160838(CHEMBL365198 | N-Methyl-N-[(S)-1-(3-nitro-phenyl)-...)
Affinity DataKi:  0.630nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM83435(2-[3-[1-[2-(3,4-dichlorophenyl)ethanoyl-methyl-ami...)
Affinity DataKi:  2.69nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160833(CHEMBL360678 | [3-(1-{Methyl-[2-(4-trifluoromethyl...)
Affinity DataKi:  2.90nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160835(CHEMBL185554 | [3-(1-{Methyl-[2-(4-trifluoromethyl...)
Affinity DataKi:  3.70nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160839(CHEMBL181922 | N-[3-((S)-1-{Methyl-[2-(4-trifluoro...)
Affinity DataKi:  9.5nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50160841(CHEMBL362458 | {Carboxymethyl-[3-((S)-1-{methyl-[2...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of bound [3H]-diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed