Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50015781
TargetEpidermal growth factor receptor(Human)
Mcgill University/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50160900(N*4*-(3-Bromo-phenyl)-N*6*-(2-chloro-ethyl)-quinaz...)
Affinity DataIC50: 10nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50160901(N*6*-(2-Chloro-ethyl)-N*4*-(3-chloro-phenyl)-quina...)
Affinity DataIC50: 26nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3294(CHEMBL52765 | 4-N-(3-bromophenyl)quinazoline-4,6-d...)
Affinity DataIC50: 44nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133382(CHEMBL343352 | N4-(3-chlorophenyl)-4,6-quinazoline...)
Affinity DataIC50: 200nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed