Compile Data Set for Download or QSAR
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Found 12 Enz. Inhib. hit(s) with all data for entry = 50015785
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50154496((R)-5-(4-Bromo-benzyl)-3-(3,5-dichloro-phenyl)-1,5...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160927((6S,7aS)-6-(4''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...)
Affinity DataIC50:  85nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160919((6S,7aS)-6-[(4''-Bromo-biphenyl-3-ylmethyl)-methyl...)
Affinity DataIC50:  175nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160925(3''-{[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-h...)
Affinity DataIC50:  175nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160924(3''-[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-he...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160920((6R,7aS)-6-(4''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...)
Affinity DataIC50:  275nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160929((6S,7aS)-6-(4''-Bromo-biphenyl-3-ylmethylsulfanyl)...)
Affinity DataIC50:  290nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160923((6S,7aS)-6-(4''-Bromo-biphenyl-4-yloxy)-2-(3,5-dic...)
Affinity DataIC50:  480nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160928((6R,7aR)-6-(4''-Chloro-biphenyl-3-ylmethoxy)-2-(3,...)
Affinity DataIC50:  620nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160926(3''-({[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-...)
Affinity DataIC50:  730nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160921((6S,7aS)-6-(3''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...)
Affinity DataIC50:  755nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160920((6R,7aS)-6-(4''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...)
Affinity DataIC50:  935nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed