Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50000441
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003896((DDATHF) 5,10-Dideazatetrahydrofolic acid2-{4-[2-(...)
Affinity DataIC50: 220nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50422000(DIDEAZAACYCLOTETRAHYDROFOLIC ACID)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005733(CHEMBL30842 | 2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihyd...)
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520(2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005731(CHEMBL31176 | 2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihyd...)
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005735(CHEMBL285232 | 2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihy...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005737(CHEMBL31609 | 2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihyd...)
Affinity DataIC50: 5.30E+3nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005728(CHEMBL30301 | 2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihyd...)
Affinity DataIC50: 6.10E+3nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005736(CHEMBL417304 | 2-{2-Chloro-4-[3-(2,4-diamino-6-oxo...)
Affinity DataIC50: 6.60E+3nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005729(CHEMBL30364 | 2-{4-[4-(2,4-Diamino-6-oxo-1,6-dihyd...)
Affinity DataIC50: 1.82E+4nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005734(CHEMBL29713 | 2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihyd...)
Affinity DataIC50: 1.87E+4nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005739(CHEMBL31027 | 2-{4-[3-(4-Amino-6-oxo-1,6-dihydro-p...)
Affinity DataIC50: 5.20E+4nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520(2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5...)
Affinity DataIC50: 9.40E+4nMAssay Description:In vitro inhibitory activity against MOLT-4 T-cell leukemia cell AICAR transformylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005738(CHEMBL31107 | 2-{4-[3-(3-Amino-5-oxo-2,5-dihydro-[...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003896((DDATHF) 5,10-Dideazatetrahydrofolic acid2-{4-[2-(...)
Affinity DataIC50: 1.30E+5nMAssay Description:In vitro inhibitory activity against MOLT-4 T-cell leukemia cell AICAR transformylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed