Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50037555
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  3.30nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13057(CHEMBL417656 | Cyclic Sulfate Analogue of Topirama...)
Affinity DataKi:  12nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13057(CHEMBL417656 | Cyclic Sulfate Analogue of Topirama...)
Affinity DataKi:  12nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  18nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13057(CHEMBL417656 | Cyclic Sulfate Analogue of Topirama...)
Affinity DataKi:  38nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13057(CHEMBL417656 | Cyclic Sulfate Analogue of Topirama...)
Affinity DataKi:  38nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163317(Sulfamic acid chroman-2-ylmethyl ester | (3,4-dihy...)
Affinity DataIC50: 130nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163318(Sulfamic acid benzo[1,3]dioxol-2-ylmethyl ester | ...)
Affinity DataIC50: 280nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataKi:  430nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataKi:  430nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataKi:  500nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataKi:  500nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition concentration against carbonic anhydrase II in rat determined in esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163316(N-{[(3aR,5aS,8aS,8bS)-7,7-dimethyl-2,2-dioxidotetr...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163316(N-{[(3aR,5aS,8aS,8bS)-7,7-dimethyl-2,2-dioxidotetr...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163319(N-(3,4-dihydro-2H-chromen-2-ylmethyl)sulfamide | S...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163315(Sulfamic acid benzo[1,3]dioxol-2-ylmethyl amine | ...)
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13055(amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13055(amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...)
Affinity DataKi:  6.50E+5nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed