Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50016041
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164212(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164210(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164213(2-Methyl-2-(4-propionyl-2,6-dipropyl-phenoxy)-prop...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164214(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164213(2-Methyl-2-(4-propionyl-2,6-dipropyl-phenoxy)-prop...)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164208(2-(3-Methoxy-5,7-dipropyl-benzo[d]isoxazol-6-yloxy...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164210(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164208(2-(3-Methoxy-5,7-dipropyl-benzo[d]isoxazol-6-yloxy...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164214(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164211(2-Methyl-2-(7-propyl-3-trifluoromethyl-benzo[d]iso...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164211(2-Methyl-2-(7-propyl-3-trifluoromethyl-benzo[d]iso...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164212(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164209(3-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164209(3-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164210(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataEC50:  300nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164214(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataEC50:  620nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164212(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataEC50:  750nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164210(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataEC50:  550nMAssay Description:Agonist activity against dog Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164213(2-Methyl-2-(4-propionyl-2,6-dipropyl-phenoxy)-prop...)
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164210(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataEC50:  460nMAssay Description:Agonist activity against hamster Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164213(2-Methyl-2-(4-propionyl-2,6-dipropyl-phenoxy)-prop...)
Affinity DataEC50:  10nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataEC50:  1.50E+4nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164208(2-(3-Methoxy-5,7-dipropyl-benzo[d]isoxazol-6-yloxy...)
Affinity DataEC50:  60nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164208(2-(3-Methoxy-5,7-dipropyl-benzo[d]isoxazol-6-yloxy...)
Affinity DataEC50:  1.10E+3nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164210(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataEC50:  180nMAssay Description:Agonist activity against mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed