Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50016188
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166087BDBM50166087(N-{3-[(2R,5S,8S,14R)-5-(3-Guanidino-propyl)-14-(4-...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166106BDBM50166106(cyclo(-D-Tyr-Arg-Arg-Nal-Gly-) | N-{3-[(2S,5S,8S,1...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166096BDBM50166096(N-[(2S,5R,11S,14S,16aS)-14-(3-Guanidino-propyl)-5-...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166079BDBM50166079(N-[(2R,5R,11S,14S,16aS)-14-(3-Guanidino-propyl)-5-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166101BDBM50166101(N-{3-[(2S,5S,11R)-14-(2-Amino-ethyl)-11-(4-hydroxy...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166086BDBM50166086(N-{3-[(2S,5S,11R)-14-(3-Amino-propyl)-11-(4-hydrox...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166093BDBM50166093(N-{3-[(2S,5S,11R,14S)-14-(2-Guanidino-ethyl)-11-(4...)
Affinity DataIC50: 24nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166080BDBM50166080(N-{4-[(2S,5S,8S,14R)-5-(3-Guanidino-propyl)-14-(4-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166094BDBM50166094(N-{3-[(2S,5S,11R,14S)-11-(4-Hydroxy-benzyl)-13,14-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166108BDBM50166108(N-{3-[(3R,6S,9S,14S)-6-(3-Guanidino-propyl)-9-(4-h...)
Affinity DataIC50: 54nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166088BDBM50166088(N-{3-[(2S,5S,11R,14R)-11-(4-Hydroxy-benzyl)-14-met...)
Affinity DataIC50: 63nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166109BDBM50166109(N-{3-[(2S,5S,11R,14R)-14-(4-Amino-butyl)-11-(4-hyd...)
Affinity DataIC50: 97nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166098BDBM50166098(3-[(2R,5S,8S,14R)-5-(3-Guanidino-propyl)-14-(4-hyd...)
Affinity DataIC50: 170nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166105BDBM50166105(N-{3-[(2S,5S,11R,14S)-11-(4-Hydroxy-benzyl)-14-met...)
Affinity DataIC50: 230nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166092BDBM50166092(2-[(2R,5S,8S,14R)-5-(3-Guanidino-propyl)-14-(4-hyd...)
Affinity DataIC50: 270nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166097BDBM50166097(N-{3-[(5R,11S,14S,16aR)-5-(4-Hydroxy-benzyl)-11-na...)
Affinity DataIC50: 420nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166102BDBM50166102(N-{3-[(2S,5S,11R,14R)-11-(4-Hydroxy-benzyl)-13,14-...)
Affinity DataIC50: 490nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166091BDBM50166091((4S,7S,10S,13R)-13-(3-Guanidino-propionylamino)-10...)
Affinity DataIC50: 530nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166107BDBM50166107(3-[(2R,5S,8S,14R)-5-(3-Guanidino-propyl)-14-(4-hyd...)
Affinity DataIC50: 610nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166090BDBM50166090((R)-13-(3-Guanidino-propionylamino)-10-(3-guanidin...)
Affinity DataIC50: 690nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166089BDBM50166089((4S,7S,10S,13R)-10-(3-Guanidino-propyl)-13-(3-guan...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166084BDBM50166084(N-{3-[(Z)-(3R,6R,9S,14R)-6-(3-Guanidino-propyl)-9-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166083BDBM50166083(N-{3-[(3R,6R,9S,14S)-6-(3-Guanidino-propyl)-9-(4-h...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166099BDBM50166099(N-{3-[(Z)-(3R,6S,9S,14R)-6-(3-Guanidino-propyl)-9-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166081BDBM50166081((4S,7S,10S,13R)-10-(3-Guanidino-propyl)-13-(3-guan...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166104BDBM50166104(N-{3-[(5R,11S,14S,16aS)-5-(4-Hydroxy-benzyl)-11-na...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166103BDBM50166103((Z)-(2S,5S,8R,13S)-13-(3-Guanidino-propionylamino)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cells; range = 1-10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166085BDBM50166085((4S,7S,10S,13R)-13-(3-Guanidino-propionylamino)-10...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166100BDBM50166100((Z)-(2S,5S,8R,14S)-14-(3-Guanidino-propionylamino)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cells; range = 1-10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166082BDBM50166082((Z)-(2S,5S,8R,13S)-13-(3-Guanidino-propionylamino)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cells; range = 1-10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166078BDBM50166078((Z)-(2S,5S,8R,15S)-15-(3-Guanidino-propionylamino)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cells; range = 1-10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166095BDBM50166095((4S,7S,10S,13R)-13-(3-Guanidino-propionylamino)-10...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]SDF-1 binding to C-X-C chemokine receptor type 4 (CXCR4) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed