Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 360
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1051BDBM1051(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.0700nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1053BDBM1053(tert-butyl N-[(2S,3S,5R)-5-{[4-(3,3-dimethoxypropy...)
Affinity DataIC50: 0.0800nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1050BDBM1050(N-[2(R)-Hydroxy-1(S)-indanyl]-5(S)-[[(1,1-dimethyl...)
Affinity DataIC50: 0.100nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1049BDBM1049(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.130nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1046BDBM1046(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.160nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1048BDBM1048(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.160nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1044BDBM1044(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.170nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1047BDBM1047(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.170nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1032BDBM1032(N-[2(R)-Hydroxy-1( S)-indanyl]-5(S)-[[(1,1-dimethy...)
Affinity DataIC50: 0.170nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1045BDBM1045(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.210nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1042BDBM1042(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.220nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 753BDBM753(Hydroxyethylene dipeptide isostere 7 | tert-butyl ...)
Affinity DataIC50: 0.230nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1030BDBM1030(tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(1...)
Affinity DataIC50: 0.230nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1031BDBM1031(N-[2(R)-Hydroxy-1(S)-indanyl]-5(S)-[[(1,1-dimethyl...)
Affinity DataIC50: 0.230nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1040BDBM1040(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.260nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1036BDBM1036(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.270nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1039BDBM1039(tert-butyl N-[(2S,3S,5R)-5-[(4-tert-butylphenyl)me...)
Affinity DataIC50: 0.270nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1038BDBM1038(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.290nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1033BDBM1033(N-[2(R)-Hydroxy-1(S)-indanyl]-5(S)-[[(1,1-dimethyl...)
Affinity DataIC50: 0.290nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1037BDBM1037(tert-butyl N-[(2S,3S,5R)-5-[(4-aminophenyl)methyl]...)
Affinity DataIC50: 0.310nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1028BDBM1028(tert-butyl N-[(2S,3S,5R)-5-{[(1S)-1-{[(1S)-1-carba...)
Affinity DataIC50: 0.360nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 751BDBM751(Hydroxyethylene dipeptide isostere | CHEMBL289195 ...)
Affinity DataIC50: 0.420nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1052BDBM1052(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.430nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1029BDBM1029(tert-butyl N-[(2S,3S,5R)-5-{[(1S)-1-{[(1S)-1-carba...)
Affinity DataIC50: 0.430nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1034BDBM1034(tert-butyl N-[(2S,3S,5R)-5-[(4-fluorophenyl)methyl...)
Affinity DataIC50: 0.440nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1043BDBM1043(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.510nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1041BDBM1041(CHEMBL47514 | tert-butyl N-[(2S,3S,5R)-3-hydroxy-5...)
Affinity DataIC50: 0.600nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1035BDBM1035(tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-{[(1S,2R)-2-h...)
Affinity DataIC50: 0.720nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1026BDBM1026(tert-butyl N-[(2S,3S,5R)-5-{[(1S)-1-{[(1S)-1-carba...)
Affinity DataIC50: 1.20nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1027BDBM1027(tert-butyl N-[(2S,3S,5R)-5-{[(1S)-1-{[(1S)-1-carba...)
Affinity DataIC50: 6nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2004
Entry Details Article
PubMed