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Found 11 Enz. Inhib. hit(s) with all data for entry = 50016349
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50118955(CHEMBL94678 | Compound K-252a(epi))
Affinity DataIC50:  1.20nMAssay Description:Inhibition of baculovirus expressed human trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50410231(CHEMBL2113064)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of baculovirus expressed human trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50410233(CHEMBL2113063)
Affinity DataIC50:  3nMAssay Description:Inhibition of baculovirus expressed human trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50167983(CHEMBL365585 | K-252a analogue)
Affinity DataIC50:  4nMAssay Description:Inhibition of baculovirus expressed human trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50167984(CHEMBL370493 | K-252a analogue)
Affinity DataIC50:  4nMAssay Description:Inhibition of baculovirus expressed human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50167984(CHEMBL370493 | K-252a analogue)
Affinity DataIC50:  4nMAssay Description:Inhibition of baculovirus expressed human trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50118955(CHEMBL94678 | Compound K-252a(epi))
Affinity DataIC50:  5nMAssay Description:Inhibition of NGF-stimulated TrkA phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  13nMAssay Description:Inhibition of baculovirus expressed human trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50410232(CHEMBL2113062)
Affinity DataIC50:  20nMAssay Description:Inhibition of baculovirus expressed human trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50410234(CHEMBL2113065)
Affinity DataIC50:  29nMAssay Description:Inhibition of baculovirus expressed human trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50167983(CHEMBL365585 | K-252a analogue)
Affinity DataIC50:  65nMAssay Description:Inhibition of baculovirus expressed human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed