Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50037508
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against HIV-1 wild type reverse transcriptase (IIIB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168052(O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against HIV-1 wild type reverse transcriptase (IIIB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103N+Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168128(O-2-(1,3-dioxoisoindolin-2-yl)ethylphenylcarbamoth...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against HIV-1 virion reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM1866(N-(2-(2-Pyridylethyl))-N -(2-(5-bromopyridyl))thio...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibitory concentration against HIV-1 wild type reverse transcriptase (IIIB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168060(N-[2-(4-Iodo-phenylthiocarbamoyloxy)-ethyl]-phthal...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory concentration against HIV-1 wild type reverse transcriptase (IIIB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168052(O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168060(N-[2-(4-Iodo-phenylthiocarbamoyloxy)-ethyl]-phthal...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM1866(N-(2-(2-Pyridylethyl))-N -(2-(5-bromopyridyl))thio...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168060(N-[2-(4-Iodo-phenylthiocarbamoyloxy)-ethyl]-phthal...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168052(O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103N+Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168060(N-[2-(4-Iodo-phenylthiocarbamoyloxy)-ethyl]-phthal...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103N+Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM1866(N-(2-(2-Pyridylethyl))-N -(2-(5-bromopyridyl))thio...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103N+Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM1866(N-(2-(2-Pyridylethyl))-N -(2-(5-bromopyridyl))thio...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168052(O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)