Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50016426
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24996BDBM24996(4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168854BDBM50168854(4-(1-Ethyl-7-piperazin-1-ylmethyl-1H-imidazo[4,5-c...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168577BDBM50168577(4-(1-Cyclopropyl-1H-imidazo[4,5-c]pyridin-2-yl)-fu...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168858BDBM50168858((R,S)-4-(1-Piperidin-3-yl-1H-imidazo[4,5-c]pyridin...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168856BDBM50168856(4-[1-(3-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyrid...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168587BDBM50168587(4-(1-Cyclohexyl-1H-imidazo[4,5-c]pyridin-2-yl)-fur...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168869BDBM50168869(1-[2-(4-Amino-furazan-3-yl)-1-ethyl-1H-imidazo[4,5...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14032BDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168861BDBM50168861(4-(4-Chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168862BDBM50168862(4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyrid...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168581BDBM50168581(4-(1-Phenyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168853BDBM50168853(4-(1-Ethyl-7-piperidin-1-ylmethyl-1H-imidazo[4,5-c...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168866BDBM50168866(4-(1-Ethyl-4-methyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168867BDBM50168867(4-(7-Bromo-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-...)
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168864BDBM50168864((R,S)-4-[1-(2-Amino-1-methyl-ethyl)-1H-imidazo[4,5...)
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168868BDBM50168868(4-[1-(4-Amino-butyl)-1H-imidazo[4,5-c]pyridin-2-yl...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14032BDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against selected kinase ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168601BDBM50168601(4-(1-Piperidin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168859BDBM50168859(4-[1-(3-Amino-propyl)-1H-imidazo[4,5-c]pyridin-2-y...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14032BDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against selected kinase p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24996BDBM24996(4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against selected kinase ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14032BDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against selected kinase DYRK1-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14032BDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Affinity DataIC50: 169nMAssay Description:Inhibitory concentration against selected kinase CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168863BDBM50168863(4-(4-Ethoxy-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50: 174nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168855BDBM50168855(4-(1-Ethyl-4-methoxy-1H-imidazo[4,5-c]pyridin-2-yl...)
Affinity DataIC50: 209nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168865BDBM50168865(4-(1,4-Diethyl-1H-imidazo[4,5-c]pyridin-2-yl)-fura...)
Affinity DataIC50: 229nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24996BDBM24996(4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...)
Affinity DataIC50: 270nMAssay Description:Inhibitory concentration against selected kinase p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168852BDBM50168852(4-[1-(3-Dimethylamino-propyl)-1H-imidazo[4,5-c]pyr...)
Affinity DataIC50: 617nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168857BDBM50168857(4-(1-Ethyl-4-phenyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Affinity DataIC50: 813nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168870BDBM50168870(4-(1-Ethyl-4-pyrrolidin-1-yl-1H-imidazo[4,5-c]pyri...)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 24996BDBM24996(4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory concentration against selected kinase DYRK1-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168860BDBM50168860(4-(1-Ethyl-4-phenoxy-1H-imidazo[4,5-c]pyridin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24996BDBM24996(4-{1-ethyl-7-[(piperidin-4-ylamino)methyl]-1H-imid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against selected kinase CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed