Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50037513
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2483BDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataEC50:  4nMAssay Description:Concentration required to inhibit HIV-1 reverse transcriptase activity (wild-type) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169065BDBM50169065(2-Methyl-5-nitro-1-[2-(phenyl-thiophen-2-yl-methox...)
Affinity DataEC50:  30nMAssay Description:Concentration required to inhibit HIV-1 reverse transcriptase activity (wild-type) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1434BDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataEC50:  250nMAssay Description:Concentration required to inhibit HIV-1 reverse transcriptase activity (wild-type) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169066BDBM50169066(1-(2-Benzhydrylsulfanyl-ethyl)-2-methyl-5-nitro-1H...)
Affinity DataEC50:  2.30E+3nMAssay Description:Concentration required to inhibit HIV-1 reverse transcriptase activity of wild-type enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169063BDBM50169063(Benzhydryl-[2-(2-methyl-5-nitro-imidazol-1-yl)-eth...)
Affinity DataEC50:  8.00E+3nMAssay Description:Concentration required to inhibit HIV-1 reverse transcriptase activity (wild-type) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed