Compile Data Set for Download or QSAR
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Found 24 Enz. Inhib. hit(s) with all data for entry = 50016462
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169361(3-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol...)
Affinity DataIC50:  3.30nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169346(5-(3-Isopropyl-2-oxo-2,3-dihydro-1H-benzoimidazol-...)
Affinity DataIC50:  4.70nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169354(5-(3-Cyclopentyl-2-oxo-2,3-dihydro-1H-benzoimidazo...)
Affinity DataIC50:  5.60nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169352(3-(3-Cyclopentyl-2-oxo-2,3-dihydro-1H-benzoimidazo...)
Affinity DataIC50:  5.70nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219259(5-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol...)
Affinity DataIC50:  10.9nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169355(1-Methyl-5-(2-oxo-3-pentyl-2,3-dihydro-1H-benzoimi...)
Affinity DataIC50:  11.7nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169359(5-(3-Isopropyl-2-oxo-2,3-dihydro-1H-benzoimidazol-...)
Affinity DataIC50:  24.8nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169345(3-Fluoro-5-(2-oxo-3-pentyl-2,3-dihydro-1H-benzoimi...)
Affinity DataIC50:  29nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169340(3-Fluoro-5-(3-isopropyl-2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  29.6nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169358(2-Fluoro-5-(3-isopropyl-2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  60.3nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169350(6-(3-Fluoro-phenyl)-1-isopropyl-1,3-dihydro-benzoi...)
Affinity DataIC50:  77.9nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169341(3-(3-Cyclohexyl-2-oxo-2,3-dihydro-1H-benzoimidazol...)
Affinity DataIC50:  83.6nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169357(1-Cyclopentyl-6-(3,4-difluoro-phenyl)-1,3-dihydro-...)
Affinity DataIC50:  96.8nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169344(6-(3,5-Dichloro-phenyl)-1-isopropyl-1,3-dihydro-be...)
Affinity DataIC50:  100nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169343(6-(3-Chloro-4-fluoro-phenyl)-1-isopropyl-1,3-dihyd...)
Affinity DataIC50:  106nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169348(6-(3-Chloro-4-fluoro-phenyl)-1-cyclobutyl-1,3-dihy...)
Affinity DataIC50:  106nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169342(6-(3-Chloro-4-fluoro-phenyl)-1-cyclopentyl-1,3-dih...)
Affinity DataIC50:  135nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169363(3-Fluoro-5-(2-oxo-3-phenyl-2,3-dihydro-1H-benzoimi...)
Affinity DataIC50:  137nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169349(1-Cyclobutyl-6-(3,4-difluoro-phenyl)-1,3-dihydro-b...)
Affinity DataIC50:  175nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169356(6-(3,4-Difluoro-phenyl)-1-isopropyl-1,3-dihydro-be...)
Affinity DataIC50:  207nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169347(6-(4-Fluoro-phenyl)-1-isopropyl-1,3-dihydro-benzoi...)
Affinity DataIC50:  295nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169362(6-(2-Fluoro-phenyl)-1-isopropyl-1,3-dihydro-benzoi...)
Affinity DataIC50:  412nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169360(6-(3-Chloro-4-fluoro-phenyl)-1-pentyl-1,3-dihydro-...)
Affinity DataIC50:  426nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169353(3-[3-(3-Chloro-phenyl)-2-oxo-2,3-dihydro-1H-benzoi...)
Affinity DataIC50:  3.00E+3nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed