Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50016619
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171275(4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-1-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241125((+)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition against Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241125((+)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition against Cytochrome P450 2C9 prepared from baculovirus-infected insect cells using 7-methoxy-4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171277([4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition against Cytochrome P450 2C9 prepared from baculovirus-infected insect cells using 7-methoxy-4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241125((+)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition against Cytochrome P450 2C19 prepared from baculovirus-infected insect cells using 3-cyano-7-ethoxycoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171284(4-(5-Chloro-2-methoxy-phenyl)-3-(2-hydroxy-ethyl)-...)
Affinity DataIC50: 5.47E+3nMAssay Description:Inhibitory activity against Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241125((+)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition against Cytochrome P450 3A4 prepared from baculovirus-infected insect cells using 7-benzyloxy-4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171282(2-[4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethy...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition against Cytochrome P450 2C19 prepared from baculovirus-infected insect cells using 3-cyano-7-ethoxycoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171280(4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition against Cytochrome P450 2C19 prepared from baculovirus-infected insect cells using 3-cyano-7-ethoxycoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171278(12-Chloro-2-trifluoromethyl-5,7-dihydro-9-oxa-5-az...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibitory activity against Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171277([4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition against Cytochrome P450 3A4 prepared from baculovirus-infected insect cells using 7-benzyloxy- 4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171280(4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition against Cytochrome P450 3A4 prepared from baculovirus-infected insect cells using resorufin benzyl etherMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171282(2-[4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethy...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition against Cytochrome P450 2C9 prepared from baculovirus-infected insect cells using 7-methoxy-4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171277([4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition against Cytochrome P450 3A4 prepared from baculovirus-infected insect cells using resorufin benzyl etherMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171280(4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)-...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition against Cytochrome P450 2C9 prepared from baculovirus-infected insect cells using 7-methoxy-4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171283(2-Chloro-6-(2-oxo-propyl)-11-trifluoromethyl-6,8-d...)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibitory activity against Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171277([4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition against Cytochrome P450 2D6 prepared from baculovirus-infected insect cells using 3-[2-(N,N-diethyl-N-methylamino)ethyl]-7- methoxy-4-meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171277([4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition against Cytochrome P450 2C19 prepared from baculovirus-infected insect cells using 3-cyano-7-ethoxycoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171282(2-[4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethy...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition against Cytochrome P450 3A4 prepared from baculovirus-infected insect cells using 7-benzyloxy- 4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171280(4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition against Cytochrome P450 3A4 prepared from baculovirus-infected insect cells using 7-benzyloxy- 4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241125((+)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition against Cytochrome P450 1A2 prepared from baculovirus-infected insect cells using 3-cyano-7-ethoxycoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241125((+)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition against Cytochrome P450 2D6 prepared from baculovirus-infected insect cells using 3-[2-(N,N-diethyl-N-methylamino)ethyl]-7-methoxy-4-methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171279(4-(5-Chloro-2-hydroxy-phenyl)-3-[3-((S)-diethyl-am...)
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibitory activity against Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171277([4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition against Cytochrome P450 1A2 prepared from baculovirus-infected insect cells using 3-cyano-7-ethoxycoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171282(2-[4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition against Cytochrome P450 3A4 prepared from baculovirus-infected insect cells using resorufin benzyl etherMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171276(4-(5-Chloro-2-hydroxy-phenyl)-3-[3-((R)-diethyl-am...)
Affinity DataIC50: 5.07E+4nMAssay Description:Inhibitory activity against Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171280(4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against Cytochrome P450 2D6 prepared from baculovirus-infected insect cells using 3-[2-(N,N-diethyl-N-methylamino)ethyl]-7- methoxy-4-meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171282(2-[4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against Cytochrome P450 2D6 prepared from baculovirus-infected insect cells using 3-[2-(N,N-diethyl-N-methylamino)ethyl]-7- methoxy-4-meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241125((+)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against Cytochrome P450 3A4 prepared from baculovirus-infected insect cells using resorufin benzyletherMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171281(1-(4-Benzyl-2-oxo-1,2-dihydro-quinolin-3-yl)-pyrid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171280(4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against Cytochrome P450 1A2 prepared from baculovirus-infected insect cells using 3-cyano-7-ethoxycoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171282(2-[4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against Cytochrome P450 1A2 prepared from baculovirus-infected insect cells using 3-cyano-7-ethoxycoumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed