Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 2412
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  20nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  30nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20156(Substituted Maleimide, 4 | 1-benzyl-3-[(4-methoxyp...)
Affinity DataEC50:  40nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20156(Substituted Maleimide, 4 | 1-benzyl-3-[(4-methoxyp...)
Affinity DataEC50:  50nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  55nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20157(GSK3987 Analogue | 1-benzyl-3-phenyl-4-(phenylamin...)
Affinity DataEC50:  70nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  80nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20157(GSK3987 Analogue | 1-benzyl-3-phenyl-4-(phenylamin...)
Affinity DataEC50:  100nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20158(GSK3987 Analogue | 1-benzyl-3-[(4-chlorophenyl)ami...)
Affinity DataEC50:  110nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20158(GSK3987 Analogue | 1-benzyl-3-[(4-chlorophenyl)ami...)
Affinity DataEC50:  130nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20159(1-ethyl-3-[(4-methoxyphenyl)amino]-4-phenyl-2,5-di...)
Affinity DataEC50:  200nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20160(3-[(4-methoxyphenyl)amino]-1,4-diphenyl-2,5-dihydr...)
Affinity DataEC50:  260nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20160(3-[(4-methoxyphenyl)amino]-1,4-diphenyl-2,5-dihydr...)
Affinity DataEC50:  275nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20159(1-ethyl-3-[(4-methoxyphenyl)amino]-4-phenyl-2,5-di...)
Affinity DataEC50:  300nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20161(3-[(4-methoxyphenyl)amino]-1-methyl-4-phenyl-2,5-d...)
Affinity DataEC50:  300nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20162(GSK3987 Analogue | 1-ethyl-3-phenyl-4-(phenylamino...)
Affinity DataEC50:  560nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20161(3-[(4-methoxyphenyl)amino]-1-methyl-4-phenyl-2,5-d...)
Affinity DataEC50:  575nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20163(3-[(4-chlorophenyl)amino]-1-ethyl-4-phenyl-2,5-dih...)
Affinity DataEC50:  575nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20163(3-[(4-chlorophenyl)amino]-1-ethyl-4-phenyl-2,5-dih...)
Affinity DataEC50:  725nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM8293(JMC485419 Compound 12 | 1-methyl-3-phenyl-4-(pheny...)
Affinity DataEC50:  850nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20162(GSK3987 Analogue | 1-ethyl-3-phenyl-4-(phenylamino...)
Affinity DataEC50:  890nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM8293(JMC485419 Compound 12 | 1-methyl-3-phenyl-4-(pheny...)
Affinity DataEC50:  1.59E+3nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed