Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 2153
LigandPNGBDBM17461(5-(4-iodophenyl)-1H-1,2,3-triazole | 1,2,3-triazol...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17468(5-(3,4-dibromophenyl)-1H-1,2,3-triazole | 1,2,3-tr...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17474(4-methyl-2-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3...)
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17460(5-(4-bromophenyl)-1H-1,2,3-triazole | 1,2,3-triazo...)
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17467(5-(3-bromophenyl)-1H-1,2,3-triazole | 1,2,3-triazo...)
Affinity DataKi:  4nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17473(3-methyl-2-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3...)
Affinity DataKi:  6nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17459(5-(4-chlorophenyl)-1H-1,2,3-triazole | 1,2,3-triaz...)
Affinity DataKi:  6nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17475(5-methyl-2-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17469(5-(1-benzofuran-2-yl)-1H-1,2,3-triazole | 1,2,3-tr...)
Affinity DataKi:  13nM ΔG°:  -44.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17447(5-(4-methylphenyl)-1H-1,2,3-triazole | 1,2,3-triaz...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17466(5-(3-iodophenyl)-1H-1,2,3-triazole | 1,2,3-triazol...)
Affinity DataKi:  16nM ΔG°:  -44.0kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17462(CHEMBL194853 | 5-(3-methylphenyl)-1H-1,2,3-triazol...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17465(N-benzyl-3-(1H-1,2,3-triazol-5-yl)aniline | 1,2,3-...)
Affinity DataKi:  29nM ΔG°:  -42.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17455(5-(4-ethylphenyl)-1H-1,2,3-triazole | 1,2,3-triazo...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17470(2-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3-triazole...)
Affinity DataKi:  41nM ΔG°:  -41.7kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17476(2-methyl-6-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3...)
Affinity DataKi:  52nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17449(1H,4H-indeno[1,2-d][1,2,3]triazole | 1,2,3-triazol...)
Affinity DataKi:  52nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17448(5-phenyl-1H-1,2,3-triazole | 1,2,3-triazole analog...)
Affinity DataKi:  70nM ΔG°:  -40.4kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17452(5-(2-methylphenyl)-1H-1,2,3-triazole | 1,2,3-triaz...)
Affinity DataKi:  112nM ΔG°:  -39.3kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17453(5-(2-methoxyphenyl)-1H-1,2,3-triazole | 1,2,3-tria...)
Affinity DataKi:  150nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17471(3-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3-triazole...)
Affinity DataKi:  260nM ΔG°:  -37.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17464(3-(1H-1,2,3-triazol-5-yl)aniline | 1,2,3-triazole ...)
Affinity DataKi:  280nM ΔG°:  -37.0kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17450(4-(4-methylphenyl)-1H-pyrazole | pyrazole analogue...)
Affinity DataKi:  280nM ΔG°:  -37.0kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17463(3-(1H-1,2,3-triazol-5-yl)phenol | 1,2,3-triazole a...)
Affinity DataKi:  300nM ΔG°:  -36.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17458(4-(1H-1,2,3-triazol-5-yl)aniline | 1,2,3-triazole ...)
Affinity DataKi:  337nM ΔG°:  -36.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17456(5-(4-propylphenyl)-1H-1,2,3-triazole | 1,2,3-triaz...)
Affinity DataKi: >1.00E+3nM ΔG°: >-33.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17472(4-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3-triazole...)
Affinity DataKi: >1.00E+3nM ΔG°: >-33.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17457(4-(1H-1,2,3-triazol-5-yl)phenol | 1,2,3-triazole a...)
Affinity DataKi: >1.00E+3nM ΔG°: >-33.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17454(5-(2-phenylphenyl)-1H-1,2,3-triazole | 1,2,3-triaz...)
Affinity DataKi: >1.00E+3nM ΔG°: >-33.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM17451(5-(4-methylphenyl)-1H-pyrazole | pyrazole analogue...)
Affinity DatapH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed