Compile Data Set for Download or QSAR
maximum 50k data
Found 102 Enz. Inhib. hit(s) with all data for entry = 50016758
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173245(1'-cyclooctylmethyl-5-fluoro-1-methylspiro[2,3-dih...)
Affinity DataIC50:  23nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173251(1'-cyclooctylmethyl-1-methylspiro[2,3-dihydro-1H-i...)
Affinity DataIC50:  32nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173256(1'-cyclooctylmethyl-1,4-dimethylspiro[2,3-dihydro-...)
Affinity DataIC50:  37nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173275(1'-cyclooctylmethyl-1-(2-oxiranylmethyl)spiro[2,3-...)
Affinity DataIC50:  83nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173246(1'-cyclooctylmethyl-5-isopropyl-1-methylspiro[2,3-...)
Affinity DataIC50:  97nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173254(CHEMBL434944 | methyl 2-[1'-cyclooctylmethyl-2-oxo...)
Affinity DataIC50:  100nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173244(1'-cyclooctylmethyl-1-{2-hydroxy-3-[2-(1,4-oxazina...)
Affinity DataIC50:  100nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173264(CHEMBL197942 | methyl 2-[1'-[4-(tert-butyl)cyclohe...)
Affinity DataIC50:  100nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173244(1'-cyclooctylmethyl-1-{2-hydroxy-3-[2-(1,4-oxazina...)
Affinity DataIC50:  120nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173243(1-benzyl-1'-cyclooctylmethylspiro[2,3-dihydro-1H-i...)
Affinity DataIC50:  120nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173252(1'-cyclooctylmethyl-6-hydroxy-1-methylspiro[2,3-di...)
Affinity DataIC50:  120nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173266(CHEMBL264066 | methyl 2-[2-oxo-1'-(3-trifluorometh...)
Affinity DataIC50:  140nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173268(1'-cyclooctylmethyl-1,6-dimethylspiro[2,3-dihydro-...)
Affinity DataIC50:  150nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173253(2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-i...)
Affinity DataIC50:  180nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173269(1'-cyclooctylmethyl-1-[3-ethyl(4-methylbenzyl)amin...)
Affinity DataIC50:  220nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173271(CHEMBL444620 | methyl 2-[1'-(2-naphthylmethyl)-2-o...)
Affinity DataIC50:  250nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173245(1'-cyclooctylmethyl-5-fluoro-1-methylspiro[2,3-dih...)
Affinity DataIC50:  250nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173267(1'-cyclooctylmethyl-1-(2-hydroxyethyl)spiro[2,3-di...)
Affinity DataIC50:  290nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173252(1'-cyclooctylmethyl-6-hydroxy-1-methylspiro[2,3-di...)
Affinity DataIC50:  300nMAssay Description:Binding affinity against human opioid receptor delta 1 expressed in HEK293 cells using [3H]DDPDE radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173269(1'-cyclooctylmethyl-1-[3-ethyl(4-methylbenzyl)amin...)
Affinity DataIC50:  320nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173281(CHEMBL198046 | methyl 2-[1'-(1,2-dihydro-5-acenaph...)
Affinity DataIC50:  350nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173247(1'-cyclooctylmethylspiro[2,3-dihydro-1H-indole-3,4...)
Affinity DataIC50:  380nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173247(1'-cyclooctylmethylspiro[2,3-dihydro-1H-indole-3,4...)
Affinity DataIC50:  430nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173250(1'-cyclooctylmethyl-1,5-dimethylspiro[2,3-dihydro-...)
Affinity DataIC50:  450nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173280(CHEMBL198678 | methyl 2-[1'-(1-naphthylmethyl)-2-o...)
Affinity DataIC50:  470nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173256(1'-cyclooctylmethyl-1,4-dimethylspiro[2,3-dihydro-...)
Affinity DataIC50:  480nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173275(1'-cyclooctylmethyl-1-(2-oxiranylmethyl)spiro[2,3-...)
Affinity DataIC50:  480nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173244(1'-cyclooctylmethyl-1-{2-hydroxy-3-[2-(1,4-oxazina...)
Affinity DataIC50:  500nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173284(CHEMBL427010 | methyl 2-[1'-cycloheptylmethyl-2-ox...)
Affinity DataIC50:  510nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173250(1'-cyclooctylmethyl-1,5-dimethylspiro[2,3-dihydro-...)
Affinity DataIC50:  540nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173256(1'-cyclooctylmethyl-1,4-dimethylspiro[2,3-dihydro-...)
Affinity DataIC50:  560nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173274(1'-cyclooctylmethyl-1-methyl-5-trifluoromethylspir...)
Affinity DataIC50:  600nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173269(1'-cyclooctylmethyl-1-[3-ethyl(4-methylbenzyl)amin...)
Affinity DataIC50:  620nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173254(CHEMBL434944 | methyl 2-[1'-cyclooctylmethyl-2-oxo...)
Affinity DataIC50:  640nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173283(1-cyclohexylmethyl-1'-cyclooctylmethylspiro[2,3-di...)
Affinity DataIC50:  680nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173248(CHEMBL373222 | methyl 2-[1'-(4-chlorobenzyl)-2-oxo...)
Affinity DataIC50:  710nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173261(CHEMBL198099 | methyl 2-[1'-cyclohexylmethyl-2-oxo...)
Affinity DataIC50:  800nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173263(CHEMBL198167 | methyl 2-[1'-hexyl-2-oxospiro[2,3-d...)
Affinity DataIC50:  820nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173275(1'-cyclooctylmethyl-1-(2-oxiranylmethyl)spiro[2,3-...)
Affinity DataIC50:  840nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173249(CHEMBL197880 | methyl 2-[2-oxo-1'-(4-trifluorometh...)
Affinity DataIC50:  880nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173276(CHEMBL380580 | methyl 2-[2-oxo-1'-perhydro-2-napht...)
Affinity DataIC50:  900nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173251(1'-cyclooctylmethyl-1-methylspiro[2,3-dihydro-1H-i...)
Affinity DataIC50:  930nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173243(1-benzyl-1'-cyclooctylmethylspiro[2,3-dihydro-1H-i...)
Affinity DataIC50:  960nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173246(1'-cyclooctylmethyl-5-isopropyl-1-methylspiro[2,3-...)
Affinity DataIC50:  980nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173245(1'-cyclooctylmethyl-5-fluoro-1-methylspiro[2,3-dih...)
Affinity DataIC50:  1.01E+3nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173272(CHEMBL370226 | methyl 2-[2-oxo-1'-(1,2,3,4-tetrahy...)
Affinity DataIC50:  1.08E+3nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173243(1-benzyl-1'-cyclooctylmethylspiro[2,3-dihydro-1H-i...)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173247(1'-cyclooctylmethylspiro[2,3-dihydro-1H-indole-3,4...)
Affinity DataIC50:  1.11E+3nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173270(CHEMBL370782 | methyl 2-[1'-cyclododecylmethyl-2-o...)
Affinity DataIC50:  1.12E+3nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50173255(1'-cyclooctylmethyl-6-methoxy-1-methylspiro[2,3-di...)
Affinity DataIC50:  1.22E+3nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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