Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50016760
TargetProstaglandin G/H synthase 2(Mouse)
University of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173290(4-[5-(2-Fluoro-ethyl)-3-phenyl-isoxazol-4-yl]-benz...)
Affinity DataIC50: 2nMAssay Description:Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173289(2-Fluoro-4-(5-methyl-3-phenyl-isoxazol-4-yl)-benze...)
Affinity DataIC50: 2nMAssay Description:Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173288(4-(5-Fluoromethyl-3-phenyl-isoxazol-4-yl)-benzenes...)
Affinity DataIC50: 2nMAssay Description:Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173288(4-(5-Fluoromethyl-3-phenyl-isoxazol-4-yl)-benzenes...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173287(4-[3-(4-Fluoro-phenyl)-5-methyl-isoxazol-4-yl]-ben...)
Affinity DataIC50: 2nMAssay Description:Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173290(4-[5-(2-Fluoro-ethyl)-3-phenyl-isoxazol-4-yl]-benz...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed