Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50016815
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174056(Diethyl-[(S)-2-(2-fluoro-phenyl)-2-(4-methyl-piper...)
Affinity DataKi:  14nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50139027(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataKi:  14nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174055(Diethyl-[2-(2-fluoro-phenyl)-2-(4-methyl-piperazin...)
Affinity DataKi:  20nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174062(Diethyl-[2-(4-methyl-piperazin-1-yl)-3-phenyl-prop...)
Affinity DataKi:  40nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174050(Diethyl-[2-(4-methyl-piperazin-1-yl)-2-(2-trifluor...)
Affinity DataKi:  40nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174045(Diethyl-[(R)-2-(4-methyl-piperazin-1-yl)-2-phenyl-...)
Affinity DataKi:  50nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174053(Diethyl-[2-(4-methyl-piperazin-1-yl)-2-o-tolyl-eth...)
Affinity DataKi:  70nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174060([2-(2-Chloro-phenyl)-2-(4-methyl-piperazin-1-yl)-e...)
Affinity DataKi:  70nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174065(Diethyl-[2-(4-methyl-piperazin-1-yl)-2-phenyl-ethy...)
Affinity DataKi:  90nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174061([2-(2,4-Difluoro-phenyl)-2-(4-methyl-piperazin-1-y...)
Affinity DataKi:  100nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174048(N-Ethyl-N-[2-(2-fluoro-phenyl)-2-(4-methyl-piperaz...)
Affinity DataKi:  106nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174057(Diethyl-[2-(4-methyl-piperazin-1-yl)-5-phenyl-pent...)
Affinity DataKi:  110nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174054(Diethyl-[(R)-2-(2-fluoro-phenyl)-2-(4-methyl-piper...)
Affinity DataKi:  111nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174051(N,N-Diethyl-2-(2-fluoro-phenyl)-2-(4-methyl-pipera...)
Affinity DataKi:  125nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174047(Diethyl-[2-(4-methyl-piperazin-1-yl)-4-phenyl-buty...)
Affinity DataKi:  130nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174059(Diethyl-[2-(4-methyl-piperazin-1-yl)-2-(3-trifluor...)
Affinity DataKi:  150nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174052([2-(2,6-Difluoro-phenyl)-2-(4-methyl-piperazin-1-y...)
Affinity DataKi:  150nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174068(N-Ethyl-N-[2-(2-fluoro-phenyl)-2-(4-methyl-piperaz...)
Affinity DataKi:  157nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174046(Diethyl-[(S)-2-(4-methyl-piperazin-1-yl)-2-phenyl-...)
Affinity DataKi:  190nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174043(Diethyl-[2-(2-methoxy-phenyl)-2-(4-methyl-piperazi...)
Affinity DataKi:  190nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174049(Diethyl-[2-(4-methyl-piperazin-1-yl)-2-(4-trifluor...)
Affinity DataKi:  200nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174058(Ethyl-[2-(2-fluoro-phenyl)-2-(4-methyl-piperazin-1...)
Affinity DataKi:  261nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174063(N-[2-(2-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  467nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174067(N-[2-(2-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  472nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174066([2-(2-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)-e...)
Affinity DataKi:  483nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174064(1-Methyl-4-(1-phenyl-ethyl)-piperazine | CHEMBL195...)
Affinity DataKi:  700nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174044(1-Benzyl-4-methyl-piperazine | CHEMBL363603)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed